Prognostic factors for ovarian epithelial cancer in the elderly: a case-control study

International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society
Renaud SabatierFrederique Rousseau

Abstract

Ovarian cancer is the leading cause of mortality by gynecologic cancers in Western countries. Many publications have suggested that age may be an independent prognostic factor in ovarian carcinoma. There are only few data concerning the impact of treatments and geriatric features within the elderly population. We collected data of older (≥ 70 years old) patients treated in our institution for an invasive ovarian carcinoma between 1995 and 2011. First we described usual clinical and pathological features for these patients, as well as their outcome. We compared these parameters with that of young (<70 years old) patients treated during the same period. We then observed geriatric features in our set: Eastern Cooperative Oncology Group performance status, number of medications, Charlson index, body mass index, hemoglobin, and glomerular filtration rate. We finally looked for prognostic factors specific of the elderly population. One hundred nine elderly patients were identified and compared with 488 younger cases. There was no difference concerning clinicopathologic data. Surgery was more frequently complete in young women (58% vs 41.7%), and older patients received less chemotherapy courses and less taxanes (38.4% vs 67.1%). Youn...Continue Reading

References

May 1, 1993·Gynecologic Oncology·M MarkmanL Almadrones
Mar 4, 1999·Gynecologic Oncology·R E BristowB Y Karlan
Jun 22, 1999·Cancer·L R DuskaN Nikrui
Jul 8, 2000·The Oncologist·L Balducci, M Extermann
Jul 16, 2003·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Robert F OzolsUNKNOWN Gynecologic Oncology Group
Oct 31, 2003·American Journal of Obstetrics and Gynecology·Jill S Barnholtz-SloanAdnan R Munkarah
Dec 17, 2003·Gynecologic Oncology·Cynthia D O'MalleyGary S Leiserowitz
Aug 12, 2005·Annals of Oncology : Official Journal of the European Society for Medical Oncology·G FreyerE Pujade-Lauraine
Oct 22, 2005·Annals of Oncology : Official Journal of the European Society for Medical Oncology·A du BoisUNKNOWN Organizational team of the two prior International OCCC
Aug 31, 2006·Cancer·James C PavelkaAndrew J Li
Nov 4, 2006·Annals of Oncology : Official Journal of the European Society for Medical Oncology·O TrédanUNKNOWN Groupe d'Investigateurs Nationaux pour l'Etude des Cancers Ovariens
Nov 8, 2006·British Journal of Cancer·J K ChanG S Leiserowitz
Jan 19, 2007·Annals of Oncology : Official Journal of the European Society for Medical Oncology·P Zola, A Ferrero
Mar 21, 2007·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·D PectasidesM A Dimopoulos
Feb 15, 2008·Annals of Oncology : Official Journal of the European Society for Medical Oncology·S V BarrettUNKNOWN Scottish Gynaecological Cancer Trials Group
Dec 9, 2008·Gynecologic Oncology·Kellie S MatthewsRodney P Rocconi
Nov 11, 2009·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·C G GeresteinC W Burger
Jun 21, 2012·Gynecologic Oncology·Joanne KotsopoulosSteven A Narod
Aug 24, 2012·The Oncologist·Min Y TeoStuart M Lichtman
Sep 26, 2013·Annals of Oncology : Official Journal of the European Society for Medical Oncology·C FalandryG Freyer
Jan 9, 2014·CA: a Cancer Journal for Clinicians·Rebecca SiegelAhmedin Jemal

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Citations

Mar 19, 2013·The International Journal of Biochemistry & Cell Biology·L BatistaF Mechta-Grigoriou
Mar 3, 2018·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Frédéric SelleAmit M Oza
Aug 2, 2017·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Annamaria FerreroAngiolo Gadducci
Sep 22, 2019·International Journal of Clinical Oncology·Maya HanataniFumitaka Kikkawa
Mar 10, 2020·Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research·Ciro PinelliHooman Soleymani Majd
Dec 12, 2019·Japanese Journal of Clinical Oncology·Nadav MichaanMyong Cheol Lim
Jul 31, 2019·American Journal of Clinical Oncology·Vasilios PergialiotisAlexandros Rodolakis
May 10, 2017·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Laura Martín de la FuenteIngrid Hedenfalk
Jan 15, 2019·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·I C van WalreeL H van Huis-Tanja
Jun 14, 2017·Journal of Ovarian Research·Fei DengXiaoxiang Chen
Jan 26, 2020·Virchows Archiv : an International Journal of Pathology·Laura Martin de la FuenteIngrid Hedenfalk
Aug 17, 2018·Molecular and Clinical Oncology·Kenji YoshikawaToshiyuki Sumi
Aug 30, 2020·Journal of Obstetrics and Gynaecology Canada : JOGC = Journal D'obstétrique Et Gynécologie Du Canada : JOGC·Sabrina PiedimonteWalter H Gotlieb
Apr 23, 2021·JAMA Oncology·Claire FalandryUNKNOWN Groupe d’Investigateurs Nationaux pour l’Étude des Cancers de l’Ovaire et du sein (GINECO)

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