Prognostic factors for postoperative recurrence of Crohn's disease. Gruppo Italiano per lo Studio del Colon e del Retto (GISC)

Diseases of the Colon and Rectum
R CaprilliA Viscido

Abstract

Prognostic factors for postoperative recurrence of Crohn's disease (CD) have been widely investigated but not yet clearly identified. Aim of this study was, therefore, to analyze the association between demographic, clinical, laboratory, and surgical characteristics of patients and the cumulative probability of endoscopic postoperative recurrence. The study was performed in 110 patients who were enrolled in the Italian multicenter, randomized, controlled trial on the effectiveness of 5-aminosalicylic acid (5-ASA) in the prevention of postoperative recurrence in CD. Patients had undergone their first intestinal resection for CD of the terminal ileum with or without involvement of cecum ascending colon. Recurrence was defined on the basis of endoscopy. The following variables were evaluated as potential prognostic factors: gender, age, years since diagnosis, clinical course (perforative and non-perforative), Crohn's Disease Activity Index score, white blood count, erythrocyte sedimentation rate, C-reactive protein, and orosomucoids assessed before the operation. Timing of operation (elective or urgent), type of anastomosis (end-to-end, end-to-side, side-to-side), and prophylactic treatment were also evaluated. Colon ileoscopy was...Continue Reading

References

May 1, 1992·Annals of Surgery·J L CameronT M Bayless
Feb 1, 1992·Digestive Diseases and Sciences·F PalloneA Torsoli
Dec 1, 1991·Scandinavian Journal of Gastroenterology·A Wettergren, J Christiansen
Sep 1, 1991·Annals of Surgery·F MichelassiG E Block
Jan 1, 1991·The British Journal of Surgery·J G WilliamsS M Goldberg
May 1, 1990·Gastroenterology·L R SutherlandG Fick
Oct 1, 1990·Gastroenterology·P RutgeertsM Hiele
Sep 1, 1988·Endoscopy·G N TytgatW H Brummelkamp
Jul 1, 1971·Gut·F T De DombalJ C Goligher
Jun 25, 1981·The New England Journal of Medicine·M R LockF L Weakley
Sep 1, 1981·American Journal of Surgery·H S Himal, P Belliveau
Nov 1, 1980·Gut·C S Higgens, R N Allan
Mar 1, 1994·Gastroenterology·M CottoneL Pagliaro
May 1, 1994·Gut·J G Ruseler-van EmbdenL M van Lieshout

❮ Previous
Next ❯

Citations

Jan 8, 2004·Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research·Jose Maria Remes-TrochePatricio Santillan-Doherty
Jul 3, 2010·Expert Review of Clinical Immunology·Jason M Swoger, Miguel Regueiro
Jan 21, 2011·The Cochrane Database of Systematic Reviews·Morris GordonAnthony K Akobeng
Mar 9, 2012·Journal of Crohn's & Colitis·E S van LooV B Nieuwenhuijs
Dec 2, 2014·Inflammatory Bowel Diseases·Aude Bressenot, Laurent Peyrin-Biroulet
Oct 24, 2014·World Journal of Gastroenterology : WJG·Tara M Connelly, Evangelos Messaris
Jan 13, 2015·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·H MisteliR Guy
Sep 25, 2017·Journal of Pediatric Gastroenterology and Nutrition·Judy B SplawskiShehzad A Saeed
Jun 21, 2019·The Cochrane Database of Systematic Reviews·Teuta Gjuladin-HellonAnthony K Akobeng
Jul 1, 1997·Journal of Pediatric Gastroenterology and Nutrition·A Bousvaros
Jan 24, 2002·Diseases of the Colon and Rectum·M Muñoz-JuárezM R Keighley
Jul 5, 2005·World Journal of Gastroenterology : WJG·Takayuki Yamamoto
Jun 19, 2007·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·M A KurerS H Leveson
Feb 2, 2008·Digestion·Florian FroehlichJean-Jacques Gonvers
Oct 13, 2009·The Cochrane Database of Systematic Reviews·Glen DohertyAlan C Moss
Dec 3, 2010·Journal of Crohn's & Colitis·Gert Van AsscheUNKNOWN European Crohn's and Colitis Organisation (ECCO)
Dec 25, 2010·Therapeutic Advances in Gastroenterology·Ebbe Langholz
Feb 9, 2012·Alimentary Pharmacology & Therapeutics·A BuissonL Peyrin-Biroulet
May 8, 2013·Nature Reviews. Gastroenterology & Hepatology·Dario Sorrentino
Jan 15, 2000·Annals of Surgery·O BernellG Hellers
Jun 7, 2003·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·C PlatellR Woods
Mar 18, 2005·Acta chirurgica Iugoslavica·A Dziki, P Galbfach
Jun 1, 2006·Journal of Magnetic Resonance Imaging : JMRI·Waleed AjajThomas C Lauenstein
Oct 16, 2012·Expert Review of Gastroenterology & Hepatology·Jana G Hashash, Miguel D Regueiro
Jan 21, 2010·Diseases of the Colon and Rectum·Constantinos SimillisParis P Tekkis
Oct 26, 2016·Digestive Diseases and Sciences·Kyle Joshua FortinskyMark S Silverberg
Oct 23, 2019·Inflammatory Bowel Diseases·Robert P HirtenBenjamin L Cohen
May 1, 2001·Alimentary Pharmacology & Therapeutics·M Parkes, D P Jewell
Feb 16, 2005·Digestion·Florian FroehlichJean-Jacques Gonvers
Sep 2, 2004·Alimentary Pharmacology & Therapeutics·F L WoltersR W Stockbrügger
Jun 3, 2009·Expert Review of Gastroenterology & Hepatology·Sandra El-Hachem, Miguel Regueiro
May 14, 2010·Orvosi hetilap·László Lakatos, Péter László Lakatos
Apr 18, 2016·Current Gastroenterology Reports·Jana G Hashash, Miguel Regueiro
Apr 11, 2001·European Journal of Gastroenterology & Hepatology·J HinojosaJ Berenguer

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.