Prognostic Factors for Severe Coronavirus Disease 2019 in Daegu, Korea

Journal of Korean Medical Science
Jong Geol JangJune Hong Ahn

Abstract

Since its first detection in December 2019, coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 infection has spread rapidly around the world. Although there have been several studies investigating prognostic factors for severe COVID-19, there have been no such studies in Korea. We performed a retrospective observational study of 110 patients with confirmed COVID-19 hospitalized at a tertiary hospital in Daegu, Korea. Demographic, clinical, laboratory, and outcome data were collected and analyzed. Severe disease was defined as a composite outcome of acute respiratory distress syndrome, intensive care unit care, or death. Diabetes mellitus (odds ratio [OR], 19.15; 95% confidence interval [CI], 1.90-193.42; P = 0.012), body temperature ≥ 37.8°C (OR, 10.91; 95% CI, 1.35-88.36; P = 0.025), peripheral oxygen saturation < 92% (OR, 33.31; 95% CI, 2.45-452.22; P = 0.008), and creatine kinase-MB (CK-MB) > 6.3 (OR, 56.84; 95% CI, 2.64-1,223.78, P = 0.010) at admission were associated with higher risk of severe COVID-19. The likelihood of development of severe COVID-19 increased with an increasing number of prognostic factors. In conclusion, we found that diabetes mellitus, body temperature ≥ 37.8...Continue Reading

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Citations

Jul 29, 2020·Archives of Plastic Surgery·Yong-Ha Kim
Aug 30, 2020·The European Respiratory Journal·Eun Young ChoiWonhwa Lee
Nov 26, 2020·Hormones : International Journal of Endocrinology and Metabolism·Xuan LiangHaiyan Yang
Jan 27, 2021·The American Journal of the Medical Sciences·Timotius Ivan HariyantoAndree Kurniawan
Dec 8, 2020·Archives of Gerontology and Geriatrics·Timotius Ivan HariyantoAndree Kurniawan
Nov 25, 2020·Journal of Korean Medical Science·KyungHee KimKwang Sung Min
Jan 30, 2021·Epidemiology and Infection·Raymond PranataRaden Ayu Tuty Kuswardhani
Mar 10, 2021·Journal of Intensive Care Medicine·Ali A El-SolhKari A Mergenhagen
Oct 20, 2020·Journal of Ayurveda and Integrative Medicine·Jyoti Anand Joshi, Rammanohar Puthiyedath
Sep 17, 2020·BMJ Evidence-based Medicine·Preeti MalikHenry Sacks
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Apr 7, 2021·Journal of Diabetes and Metabolic Disorders·Sumanta SahaSujata Saha
Jun 3, 2021·International Journal of Environmental Research and Public Health·Ejin KimHo Kim
Mar 19, 2021·Tuberculosis and Respiratory Diseases·Kyeong-Cheol Shin
Jul 6, 2021·Anesthesiology and Pain Medicine·Katayoun HaryalchiSamaneh Ghazanfar Tehran
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Jun 18, 2021·Journal of Medical Virology·Giovanna PicchiAlessandro Grimaldi

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