Prognostic Factors in Advanced Non-Small-Cell Lung Cancer Patients: Patient Characteristics and Type of Chemotherapy

Lung Cancer International
Salah Abbasi, Ahmed Badheeb

Abstract

Eleven prognostic factors were retrospectively analyzed in 270 newly diagnosed patients with advanced non-small-cell lung cancer including age, sex, performance status, histology, stage, smoking status, hemoglobin level, forced expiratory volume in one second (FEV1), weight loss >5% in 3 months preceding therapy, number of involved organs, and type of first-line chemotherapy. Response rate was 35.6%, and median survival was 8.2 months (95% CI, 7.8 to 8.7) for the whole group. Age ≤60 years (P = .016), FEV1 ≥ 2L (P = .03), and the use of platinum/docetaxel (P < .0001) were significantly associated with an improved survival. Histology did not affect outcome in the absence of targeted therapies.

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Citations

Oct 31, 2012·Oncology Nursing Forum·Juhua LuoAlan Ducatman
Sep 25, 2018·Clinical and Experimental Immunology·D RiemannB Seliger
Oct 30, 2020·Pharmacogenomics and Personalized Medicine·Nadiya Nurul AfifahMelisa I Barliana
Nov 20, 2020·The Journal of Rural Health : Official Journal of the American Rural Health Association and the National Rural Health Care Association·Vira PravosudSusanne M Arnold
Apr 12, 2021·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Balazs HalmosBilal Piperdi
Dec 11, 2021·PloS One·Muhammad Rafiqul IslamMd Nazmul Karim

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