Prognostic factors in laryngeal squamous cell carcinoma

Laryngoscope Investigative Otolaryngology
Carol R BradfordAlessandra Rinaldo

Abstract

The current treatment results of laryngeal squamous cell carcinoma still remain modest. Various prognostic factors have been investigated and need to be included in the management decision making. We reviewed the pertinent literature regarding host, tumor, and treatment factors as prognostic indicators that influence outcome in patients diagnosed with laryngeal squamous cell carcinoma. Host, tumor, and treatment factors all have an important impact upon an individual patient's prognosis with laryngeal squamous cell carcinoma, whereas staging systems only take into account tumor factors. There is much work yet to be done to establish reliable, independent biomarkers that predict survival and response to treatment. Optimal outcomes for an individual patient can be achieved when taking into account tumor, host, and treatment factors.

References

Jan 1, 1992·ORL; Journal for Oto-rhino-laryngology and Its Related Specialties·F SilvestriA Ferlito
Jul 1, 1991·Archives of Otolaryngology--head & Neck Surgery·W T StephensonC W Norris
Apr 1, 1991·Archives of Otolaryngology--head & Neck Surgery·B J Bailey
Jun 13, 1991·The New England Journal of Medicine·UNKNOWN Department of Veterans Affairs Laryngeal Cancer Study GroupWilliam G Henderson
Feb 1, 1990·Clinical Otolaryngology and Allied Sciences·P M Stell
Apr 1, 1990·Clinical Otolaryngology and Allied Sciences·P M Stell
Oct 1, 1988·Clinical Otolaryngology and Allied Sciences·P M Stell
Jan 1, 1981·Journal of Chronic Diseases·W O SpitzerB R Catchlove
Feb 16, 1995·The New England Journal of Medicine·J A BrennanD Sidransky
Feb 1, 1994·The Annals of Otology, Rhinology, and Laryngology·J F PiccirilloA R Feinstein
Mar 1, 1993·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·D F CellaJ Brannon
Sep 26, 1997·The Annals of Otology, Rhinology, and Laryngology·C M MilroyA Rinaldo
Dec 31, 1997·The Annals of Otology, Rhinology, and Laryngology·K O DevaneyA Rinaldo
Jun 25, 1998·Archives of Otolaryngology--head & Neck Surgery·J J FaganJ T Johnson
Nov 5, 1999·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·C R BradfordS G Fisher
Feb 1, 2000·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·P D LacyM R Zequeira
Apr 14, 2000·Clinical Otolaryngology and Allied Sciences·J GreenmanN D Stafford
Oct 4, 2000·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·K NylanderP A Hall
Apr 20, 2001·Clinical Otolaryngology and Allied Sciences·A P YuenW I Wei
Dec 3, 2003·The New England Journal of Medicine·Arlene A ForastiereJay Cooper
Jan 1, 1951·Cancer·M B SHIMKIN
Dec 2, 2004·Auris, Nasus, Larynx·A N DemiralM Kinay
Apr 21, 2005·Clinical Otolaryngology : Official Journal of ENT-UK ; Official Journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery·H TeppoO-P Alho
Oct 4, 2005·Head & Neck·Juan Pablo RodrigoAlessandra Rinaldo
Dec 19, 2007·Archives of Otolaryngology--head & Neck Surgery·Amy Y Chen, Michael Halpern
Jun 3, 2009·The Laryngoscope·Jessica L BaumannRobbert J C Slebos
Sep 19, 2009·Expert Review of Anticancer Therapy·Antti A Mäkitie, Outi Monni
Jan 18, 2011·European Annals of Otorhinolaryngology, Head and Neck Diseases·E E M NaoA Bozec
Oct 19, 2011·Annals of the Royal College of Surgeons of England·C JonesR Hannon
Aug 10, 2012·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Amy Anne D LassigBevan Yueh
Nov 24, 2012·The Journal of Infectious Diseases·Xiangwei LiQi Jin
Nov 28, 2012·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Arlene A ForastiereJay S Cooper
Apr 5, 2013·Head & Neck·Naomi RabinovicsGideon Bachar
Jun 19, 2013·The Laryngoscope·Carol R BradfordThomas E Carey
Aug 21, 2013·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Charlotte Rotbøl Bøje
Apr 25, 2014·Pathology Oncology Research : POR·David KalfertMarie Ludvikova

❮ Previous
Next ❯

Citations

Dec 11, 2020·Acta otorhinolaryngologica Italica : organo ufficiale della Società italiana di otorinolaringologia e chirurgia cervico-facciale·Andy BertolinGiovanni Succo
Mar 16, 2021·Critical Reviews in Oncology/hematology·Luca Giovanni LocatelloOreste Gallo
May 1, 2021·Cancers·Nathalia Meireles Da CostaAntonio Palumbo Júnior
May 19, 2021·European Journal of Radiology·Peng WangYang Zhan
Jun 16, 2021·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Mason JohnsonAlexandra Eva Kejner
Jun 29, 2021·Frontiers in Cell and Developmental Biology·Wenlun WangLingyun Zhu
Jun 20, 2021·Brazilian Journal of Otorhinolaryngology·Akın ŞahinAbdullah Çağlar Batman
Jul 10, 2021·Annals of Diagnostic Pathology·Matteo CavaliereClaudia Cassandro

❮ Previous
Next ❯

Methods Mentioned

BETA
imaging techniques
flow cytometry
dissection
biopsy

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.