PMID: 12198211Aug 29, 2002Paper

Prognostic factors in mesangioproliferative glomerulonephritis

Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association
Bjørn Egil VikseBjarne M Iversen


The aim of our study was to examine patients with mesangioproliferative glomerulonephritis (MPGN), with or without glomerular IgA deposits, and to analyse the effect of different clinical and histopathological variables at the time of biopsy on progression to end-stage renal failure (ESRF) and death. We retrospectively examined 273 patients who got this diagnosis in Norway from April 1988 to December 1990 after a renal biopsy. All patients were followed for a median duration of 34.8 months (0.8-68 months). The mean age at the time of biopsy was 40+/-17 years (range 1.1-79 years). Glomerular IgA deposits were present in 45% of the patients; IgA deposits did not affect prognosis. Three years after the time of biopsy, 7% had developed ESRF (chronic dialysis treatment or kidney transplantation) and 8% had died. By Kaplan-Meier analyses, the following clinical variables indicated progression to ESRF: increased serum creatinine, proteinuria > or =1 g/24 h, systolic blood pressure (BP) > or =160 mmHg, diastolic BP > or =90 mmHg, serum albumin <35 g/l, presence of urinary granular casts and age > or =60 years. Morphological variables indicating progression to ESRF were presence of focal mesangial sclerosis, focal glomerular crescents o...Continue Reading


Nov 18, 2011·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Chiao-Yin SunMai-Szu Wu
Apr 4, 2012·Journal of Hypertension·Michael Hultström
Feb 26, 2008·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Silvestre García-de la PuenteBeatriz de Leon Bojorge
Feb 20, 2007·Postgraduate Medical Journal·Gerald S BraunHolger Schmid
Jul 24, 2012·Clinical and Experimental Nephrology·Takashi TakeiKosaku Nitta
Nov 15, 2011·European Journal of Internal Medicine·Pierangela PrestaGiorgio Fuiano
Oct 29, 2005·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Marie EvansC Michael Fored
Jul 10, 2003·Microcirculation : the Official Journal of the Microcirculatory Society, Inc·Ivo BuschmannWolfgang Schaper
May 28, 2013·Clinica Chimica Acta; International Journal of Clinical Chemistry·Diana SpinelliGiovanni B Fogazzi
May 7, 2016·Journal of the American Society of Nephrology : JASN·Cheng ZhuPeter R Mertens
Jul 13, 2017·American Journal of Nephrology·Yasar CaliskanMehmet Sukru Sever
Jul 11, 2006·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Kenji WakaiHideto Sakai
May 19, 2012·Paediatrics and International Child Health·Sriram KrishnamurthySadagopan Srinivasan

❮ Previous
Next ❯

Related Concepts

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.


Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.


Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation
Giovanni B FogazziDario Consonni
Annals of Internal Medicine
J R Burton, J W Rowe
Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association
Rolf E F ChristiansenBjarne M Iversen
© 2021 Meta ULC. All rights reserved