Prognostic factors in squamous cell carcinoma of the penis and implications for management

British Journal of Urology
A B AdeyojuM Butler

Abstract

To determine the clinical and pathological features, methods and outcome of management in squamous cell carcinoma of the penis (SCCP). A retrospective study was carried out of 42 patients (mean age 63 years, range 28-86) with a histological diagnosis of SCCP. The disease stage, grade, treatment of primary tumour, lymph node disease and survival were recorded; the mean follow-up was 4 years (range 1.5-25). The disease stage was T1 in 24 patients (57%), T2 in 14 (33%), T3 in three (7%) and T4 in one (2%); the tumour grade was well differentiated in 20 (47%), moderately differentiated in 14 (33%) and poorly differentiated in three (7%). Eight patients had histologically confirmed inguinal node disease at presentation, six of whom underwent lymph node dissection, while two underwent radiotherapy. Five patients developed inguinal node disease during follow-up (mean 10 months, range 4-21). Three of these patients were irradiated and two underwent lymph node dissection. Six patients (14%) had local recurrence, five of whom were managed surgically. One patient developed a local recurrence 11 years after initial surgery. Seven patients died from their disease (17%); four died within 2 years, being patients with high-stage and/or high-gr...Continue Reading

Citations

Sep 4, 2008·World Journal of Urology·Antonio L Cubilla
May 6, 2009·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Ilteris Murat Emsen
Aug 3, 2010·The Urologic Clinics of North America·Richard E Greenberg
Jul 24, 2004·Urologic Oncology·Ricardo F Sánchez-Ortiz, Curtis A Pettaway
Dec 1, 2009·Urologic Oncology·Boris SchlenkerEdwin Hungerhuber
Oct 13, 2001·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·R E EmersonL Cheng
Apr 23, 2009·The American Journal of Surgical Pathology·Alcides ChauxAntonio L Cubilla
Nov 15, 2019·Journal of Cutaneous Medicine and Surgery·François LagacéIvan V Litvinov

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carcinoma, Squamous Cell

Basal cell carcinoma is a form of malignant skin cancer found on the head and neck regions and has low rates of metastasis. Discover the latest research on basal cell carcinoma here.

Related Papers

European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
M AryaS J Harland
Urology
D P Sarma, T G Weilbaecher
British Journal of Urology
S A Rasbridge, J R Parry
© 2021 Meta ULC. All rights reserved