PMID: 7523963Jan 1, 1993Paper

Prognostic factors in the surgery for intracranial meningioma. Role of the tumoral size and arterial vascularization originating from the pia mater. Study of 150 cases

Neuro-Chirurgie
M Alaywan, M Sindou

Abstract

The authors report a series of 150 consecutive patients operated on for an intracranial meningioma over a period of 14 years (1974-1988). The patients were aged from 15 to 85 years (mean: 58 y; 49 were over 60 y) and severely disabled preoperatively in 42 cases (Karnofsky score 10 to 60). Tumors were located in the convexity in 22% the parasagittal region and falx in 24%, the skull base in 14% and the posterior fossa in 13%. In 21 cases the diameter of the tumor was less than 3 cm, in 86 it ranged from 3 to 6 cm, and in 43 cases it was more than 6 cm (29%). Tumor was hypervascularized in 51% of cases. Peritumoral edema was present in 73 of the 106 patients studied (69%). The tumor was removed completely (grade I and II of Simpson classification) in 136 cases (91%). Post-operative mortality was 10%. 88.5% of the surviving patients had a normal life with a score of 80 to 100 according to Karnofsky scale. Recurrence rate amounted at 3.3%. Mortality and severe morbidity (poor outcome) were assessed and correlated with sex, age, tumor, size, location, vascularization, peritumoral edema and histology. From this retrospective study the only predictives of a poor outcome, statistically significant, were: severe preoperative neurologica...Continue Reading

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