Abstract
Although lateralization of the brain affects some specialized cortical functions, there are still limited data to address its influence on clinically important outcomes. This study aimed to reveal the prognostic variables that relate to functional recovery in stroke patients with a left-sided hemispheric lesion during 6 months of follow-up. Data from 167 left-sided and 183 right-sided hemispheric strokes were reviewed retrospectively. Outcomes in this study included walking capacity and functional recovery, assessed by the modified Rankin Scale (mRS). In order to obtain independent predictive variables, this study used the step-backward method of multivariable regression analysis of parameters. The final model demonstrated that motor function of the hemiparetic leg was the strongest independent predictor for both walking ability and functional recovery (risk ratio (RR) of 2.41, 95% CI: 1.61-3.60, and p < 0.001 and RR of 1.83, 95% CI: 1.03-3.26, and p = 0.04, resp.). Therefore, lateralization did not seem to be involved. Understanding predictable variables that are associated with recovery can guide the rehabilitation team in setting priority and appropriate treatment for stroke patients.
References
Aug 1, 1996·Neurology·J E WeenM Roberts
Mar 1, 1997·American Journal of Physical Medicine & Rehabilitation·P M PedersenT S Olsen
Oct 21, 1998·Archives of Physical Medicine and Rehabilitation·S N MacciocchiT Mertz
Nov 5, 1999·Stroke; a Journal of Cerebral Circulation·D WooJ C Grotta
Oct 13, 2000·Archives of Physical Medicine and Rehabilitation·A T PatelS Studenski
Mar 14, 2001·Archives of Physical Medicine and Rehabilitation·L R CherneyM Zhang
May 15, 2001·Journal of Internal Medicine·A C LaskaM Von Arbin
Nov 8, 2002·Archives of Physical Medicine and Rehabilitation·Henk T HendricksMachiel J Zwarts
Jun 18, 2003·Hypertension·Sergio A Rodríguez HernándezPeter W de Leeuw
Dec 18, 2003·Neurorehabilitation and Neural Repair·Yocheved LauferElliot Sprecher
Feb 3, 2007·Stroke; a Journal of Cerebral Circulation·Jamie L Banks, Charles A Marotta
Jan 15, 2008·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Hirono ItoKen Ikeda
Nov 8, 2008·Stroke; a Journal of Cerebral Circulation·John N FinkUNKNOWN Virtual International Stroke Trials Archive Investigators
Dec 27, 2008·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Atsuko GotoGen Sobue
Apr 27, 2010·BMC Neurology·Albert J YooPamela W Schaefer
Aug 20, 2010·Cerebrovascular Diseases·Bernardo Gialanella, Cristina Ferlucci
Nov 29, 2011·Archives of Physical Medicine and Rehabilitation·Katerina HilariKirsty L Harrison
Apr 30, 2013·Journal of Clinical Neurology·Vishnumurthy Shushrutha HednaMichael F Waters
May 16, 2013·Frontiers in Human Neuroscience·Nicole Y H YangKenneth N K Fong
Mar 24, 2015·Journal of Nippon Medical School = Nippon Ika Daigaku Zasshi·Yukihiro Hara
Apr 22, 2015·Disability and Rehabilitation·Maria Stella SteinFrances Ann Reynolds
Nov 3, 2015·Physical Medicine and Rehabilitation Clinics of North America·Richard L Harvey
Nov 7, 2015·Trials·Jose Manuel Pérez-MármolMaría Encarnación Aguilar-Ferrándiz
Apr 12, 2016·Neuropsychologia·Bettina MohrYury Shtyrov
Jan 26, 2017·Annals of Rehabilitation Medicine·Gowun KimEun Kyoung Kang
Apr 1, 2015·International Journal of Stroke : Official Journal of the International Stroke Society·Myzoon AliUNKNOWN VISTA Collaboration