Prognostic factors of vitreous hemorrhage secondary to exudative age-related macular degeneration

American Journal of Ophthalmology
Tomoko HasegawaNagahisa Yoshimura

Abstract

Vitreous hemorrhage (VH) is a rare but serious complication of the eyes with exudative age-related macular degeneration (AMD). This retrospective study was designed to evaluate various clinical factors that may affect the visual prognosis of patients with VH secondary to exudative AMD. Retrospective case study. We intensively documented 31 cases of VH secondary to exudative AMD and retrospectively analyzed best-corrected visual acuity (BCVA). All eyes underwent standard pars plana vitrectomy (PPV) for treating VH. Three subgroups were created according to the clinical course and treatment history before the occurrence of VH: (1) gas group (7 eyes), pneumatic displacement with sulfur hexafluoride gas performed to treat massive submacular hemorrhage; (2) photodynamic therapy (PDT) group (9 eyes), PDT performed to treat exudative AMD; (3) untreated group (15 eyes), no treatment performed. As a whole, BCVA before the occurrence of VH was 1.05 +/- 0.59 (logarithm of the minimal angle of resolution). After the occurrence of VH, BCVA before PPV dropped to 2.61 +/- 0.82. After the operation, final BCVA improved significantly to 1.25 +/- 0.73 (P< 10(-8)). In a subgroup analysis, no statistically significant difference was seen among the...Continue Reading

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Citations

Apr 14, 2017·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Jae Hui KimChul Gu Kim
Jul 9, 2020·International Journal of Retina and Vitreous·Carsten GrohmannChristos Skevas

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