Prognostic Impact of Underweight (Body Mass Index <20 kg/m2 ) in Patients With Severe Aortic Valve Stenosis Undergoing Transcatheter Aortic Valve Implantation or Surgical Aortic Valve Replacement (from the German Aortic Valve Registry [GARY])

The American Journal of Cardiology
Lisa VoigtländerGARY Executive Board

Abstract

According to the Valve Academic Resortium, underweight is one parameter in the definition of frailty, which is associated with increased mortality after transcatheter aortic valve implantation (TAVI) and surgical aortic valve replacement (SAVR). Aims of our study were (1) to examine the impact of underweight on mortality after TAVI and SAVR and (2) to determine the effect of intervention mode (TAVI vs SAVR) on mortality in underweight patients from the German Aortic Valve Registry. Overall, 35,109 patients treated with TAVI or SAVR were studied. Outcomes of underweight (body mass index [BMI] <20 kg/m2) TAVI and SAVR patients were compared using propensity score weighting. Prevalence of underweight was 5.7% in patients who underwent TAVI and 2.9% in patients who underwent SAVR. Underweight patients had significantly increased mortality rates for both treatment strategies compared with normal weight patients (BMI 20 to 30 kg/m2). Comparing underweight TAVI and SAVR-patients using propensity score weighting, no statistically significant differences regarding mortality rates were observed. Subgroup analysis of severely underweight patients (BMI <18.5 kg/m²) revealed no significant increase of mortality after TAVI compared with unde...Continue Reading

Citations

Feb 13, 2021·Minerva medica·Nicola CorcioneUNKNOWN Registro Italiano GISE sull'impianto di Valvola Aortica Percutanea (RISPEVA) Study Investigators
Jul 25, 2021·Internal and Emergency Medicine·Fabio Alfredo SguraGiuseppe Boriani
Aug 21, 2021·Cardiovascular Revascularization Medicine : Including Molecular Interventions·Marouane BoukhrisJean-Bernard Masson

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