Prognostic implications of fragmented QRS and its relationship with delayed contrast-enhanced cardiovascular magnetic resonance imaging in patients with non-ischemic dilated cardiomyopathy

International Journal of Cardiology
Min-Soo AhnSung-Soon Kim

Abstract

We determined the relationship between fragmented QRS (fQRS) on electrocardiograms (ECG) as well as myocardial fibrosis measured by delayed enhancement of cardiac magnetic resonance imaging (DE-CMR) and its prognostic implication in patients with non-ischemic dilated cardiomyopathy (DCM). The ECGs of 86 subjects with dilated non-ischemic DCM who underwent DE-CMR were analyzed. DCM was defined as LV end-diastolic dimension >55 mm with LVEF <45% and chronic symptomatic heart failure for ≥ 9 months. Cardiac events (re-hospitalization due to heart failure, arrhythmic event, cardiac death) were reviewed retrospectively. fQRS was defined by the presence of an additional R wave (R"), or notching of the S wave, or the presence of more than one R prime in two contiguous leads. In 86 patients, fQRS developed in 53 patients (61.6%) and delayed enhancement was observed in 42 patients (48.8%). The mean ejection fraction was 25.0%. Baseline characteristics were similar in both groups. Analyses of echocardiographic parameters revealed left ventricular end-diastolic and end-systolic dimensions were significantly higher in the fQRS group, but that the left ventricular ejection fraction was not significantly different. The prevalence of delayed ...Continue Reading

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Citations

May 13, 2014·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Ki-Woon KangHye Jin Hwang
Oct 31, 2014·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·James A RosengartenJohn M Morgan
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Jul 29, 2016·Heart and Vessels·Yoshihiro TanakaKenshi Hayashi
Aug 28, 2016·The International Journal of Cardiovascular Imaging·Da-Jun HuYa-Nan Zhou
Oct 18, 2018·Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·Chanavuth KanitsoraphanSubhanudh Thavaraputta
Apr 4, 2020·European Journal of Heart Failure·Gherardo FinocchiaroGianfranco Sinagra

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