Prognostic Implications of Lymph Node Yield in Central and Lateral Neck Dissections for Well-Differentiated Papillary Thyroid Carcinoma

Thyroid : Official Journal of the American Thyroid Association
Chase M HeatonLisa A Orloff

Abstract

The aim of this study was to evaluate the relationship between lymph node yield (LNY) from central (CND) and lateral (LND) neck dissections and risk of recurrence in patients undergoing primary surgery for well-differentiated papillary thyroid carcinoma (WDPTC). Clinical data were reviewed from all patients with biopsy-proven WDPTC who underwent primary total thyroidectomy with CND or LND at the authors' institution from 2005 to 2009. Patient demographics and tumor characteristics were obtained, and clinical data with at least five-year follow-up were used. Within the CNDs and LNDs, total number of nodes removed (LNY), total positive nodes removed, and the ratio of positive lymph nodes to LNY were determined. One hundred fifty-two patients were included in the study, with average follow-up of 69 months. Of 125 patients who underwent CND, 20 had central neck disease recurrence. The LNY of patients with central neck recurrence was significantly less than those who had no recurrence (2.5 vs. 10.3; p < 0.0001). Of 71 patients who underwent LND, 23 had ipsilateral lateral neck disease recurrence. The LNY of patients with lateral neck recurrence was significantly less than those who did not recur (10.5 vs. 24.6; p < 0.0001). Higher r...Continue Reading

References

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Citations

Nov 10, 2017·Thyroid : Official Journal of the American Thyroid Association·Sung Hoon NamSang Yoon Kim
Jul 18, 2017·JAMA Otolaryngology-- Head & Neck Surgery·Jon Mallen-St Clair
Dec 2, 2017·JAMA Otolaryngology-- Head & Neck Surgery·Moran AmitMark E Zafereo
Feb 19, 2020·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Shaunak N AminSarah L Rohde
Oct 30, 2019·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Julia E Noel, Lisa A Orloff
Oct 23, 2020·Ear, Nose, & Throat Journal·Khalil IssaDaniel J Rocke
Oct 28, 2021·Annals of Surgical Oncology·Jennifer SiuAntoine Eskander

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Methods Mentioned

BETA
dissection
dissections
biopsy
neck

Software Mentioned

SAS

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