Prognostic implications of normal (<0.10 ng/ml) and borderline (0.10 to 1.49 ng/ml) troponin elevation levels in critically ill patients without acute coronary syndrome

The American Journal of Cardiology
Russell SteinCalvin Eng

Abstract

Borderline increase of troponin I (cTnI) is associated with higher rates of cardiovascular events compared with normal levels in the setting of acute coronary syndrome (ACS), but the significance of borderline cTnI levels in patients without chest pain may differ. The aim of this study was to determine the prognostic implications of intermediate serum cTnI levels in patients without ACS in the intensive care unit (ICU). This was a 12-month retrospective study of 240 patients without ACS in the ICU with normal (<0.1 ng/ml) or intermediate (0.1 to 1.49 ng/ml) cTnI levels. End points included in-hospital mortality, lengths of ICU and hospital stays, and rates of postdischarge readmission and mortality. Overall in-hospital mortality was 13%, with 5% in the normal cTnI group and 28% in the intermediate cTnI group. By multivariate analysis, intermediate cTnI was independently associated with in-hospital mortality (p = 0.004) and length of ICU stay (p = 0.028). The only other independent risk factor for inpatient mortality was a standardized ICU prognostic measurement (Simplified Acute Physiology Score II score). Intermediate cTnI had no prognostic implications regarding length of hospital stay, readmission rate, or postdischarge mort...Continue Reading

References

Jun 12, 2003·Journal of the American College of Cardiology·Peter AmmannThomas Fehr
Sep 3, 2005·Critical Care : the Official Journal of the Critical Care Forum·Daniel A KingYaniv Almog

❮ Previous
Next ❯

Citations

Feb 16, 2013·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Sean M BagshawLakhmir S Chawla
Dec 19, 2015·Journal of Veterinary Internal Medicine·R Langhorn, J L Willesen
Aug 9, 2011·Journal of Veterinary Cardiology : the Official Journal of the European Society of Veterinary Cardiology·Joann SlackVirginia Reef
Feb 13, 2010·Journal of Critical Care·Jijo JohnDarell Heiselman
Sep 29, 2009·Journal of Critical Care·Wendy LimDeborah Cook
May 24, 2011·The American Journal of Medicine·Edward O McFallsPatricia L Sinnott
Jul 7, 2009·The American Journal of Cardiology·Usman JavedDeepak Thatai
Apr 19, 2015·Critical Care : the Official Journal of the Critical Care Forum·Lakhmir S ChawlaClaudio Ronco
Mar 10, 2016·World Journal for Pediatric & Congenital Heart Surgery·David S CooperCatherine D Krawczeski
Sep 21, 2013·Biomarker Insights·Antoine KossaifyUNKNOWN STAR-P Consortium
Mar 20, 2010·Clinical Journal of the American Society of Nephrology : CJASN·Stuart L Goldstein, Lakhmir S Chawla
Mar 29, 2014·Clinical Journal of the American Society of Nephrology : CJASN·Dinna N CruzUNKNOWN NEFROINT Investigators
Mar 29, 2014·Clinical Journal of the American Society of Nephrology : CJASN·Rajit K BasuStuart L Goldstein
May 24, 2011·Critical Care Medicine·Jeffrey C Trost, Richard A Lange
Jul 1, 2011·Current Opinion in Critical Care·Nikolaos MarkouPavlos Myrianthefs
Oct 2, 2015·Journal of Investigative Medicine : the Official Publication of the American Federation for Clinical Research·Stacy PoeFlorence G Rothenberg
Feb 7, 2020·The American Journal of Emergency Medicine·Holly R HansonRajit K Basu

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.

Cardiovascular Diseases: Risk Factors

Cardiovascular disease is a significant health concern. Risk factors include hypertension, obesity, dyslipidemia and smoking. Women who are postmenopausal are at an increased risk of heart disease. Here is the latest research for risk factors of cardiovascular disease.

© 2022 Meta ULC. All rights reserved