PMID: 3756793Oct 15, 1986Paper

Prognostic importance of progesterone and estrogen receptors in cancer of the uterine cervix

Cancer
R A PotishB S Leung

Abstract

Tissue levels of cytosolic estrogen receptors (ERc) and progesterone receptors (PRc) have been shown to have prognostic meaning in hormonally responsive cancers arising in the breast and endometrium. Although carcinomas of the uterine cervix rarely respond to hormonal manipulation, the normal cervical stroma and epithelia contain ERc and PRc. To study the prognostic value of these receptors, 65 cervical carcinomas for ERc and PRc were assayed before initiation of surgical or radiation therapy. In premenopausal women, logistic models demonstrated that clinical stage, surgical stage, and receptor level independently predict survival. If confirmed in further studies, ERc and PRc may prove to be useful prognostic factors in the management of cervical carcinomas.

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Citations

Sep 24, 1999·Diagnostic Cytopathology·D Vinette-LeducN Villeneuve
May 1, 1995·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·A W FylesG A Rawlings
Jan 21, 2004·Nature Reviews. Cancer·Andrew P Feinberg, Benjamin Tycko
Dec 2, 2004·Nature Reviews. Cancer·Jean-Pierre Issa
Mar 11, 1992·Critical Reviews in Oncology/hematology·D N Danforth
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May 5, 2017·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Mun-Kun HongTang-Yuan Chu
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Jan 1, 1992·Journal of Tongji Medical University = Tong Ji Yi Ke Da Xue Xue Bao·H X AnG R Cai

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