PMID: 7370564Feb 23, 1980Paper

Prognostic importance of specific immunoreactivity in occupational bladder cancer

British Medical Journal
S KumarW Hurst

Abstract

Sixty-eight workers with a history of exposure to a bladder carcinogen were followed up to see whether changes in lymphocyte immunoreactivity to a bladder-cancer-cell target were predictive of the development of neoplasia of the urothelium. A twofold or greater increase in reactivity was strongly associated with the development of abnormal urinary cytology suggestive or indicative of malignant change. Changes in immunoreactivity to a non-bladder-cancer-cell target did not have this association. The findings support the possibility that changes in lymphocyte immunoreactivity may be used to predict the onset of bladder cancer in people exposed to bladder carcinogens.

References

Apr 15, 1979·International Journal of Cancer. Journal International Du Cancer·G TaylorG H Shaw
Mar 1, 1970·Transplantation·M Takasugi, E Klein

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Citations

May 3, 1986·British Medical Journal·W R Lee
May 1, 1981·British Journal of Industrial Medicine·S KumarC B Costello
May 1, 1990·British Journal of Industrial Medicine·T TanigawaN Minato

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