Prognostic predictors in non-small cell lung cancer patients undergoing intentional segmentectomy

The Annals of Thoracic Surgery
Terumoto KoikeShin-ichi Toyabe

Abstract

Despite recent studies reporting on the results of prospective intentional sublobar resection for patients with small non-small cell lung cancer (NSCLC), few studies have investigated predictors for prognosis or recurrence exclusively in patients undergoing intentional sublobar resection. We retrospectively reviewed 223 patients with small (2 cm or less) peripheral NSCLC who underwent intentional segmentectomy at the Niigata Cancer Center Hospital between 1992 and 2009. The significant demographic, clinical, and pathologic factors identified with the log rank test in univariate analyses were analyzed with the Cox proportional hazards regression model to examine independent predictors for prognosis and recurrence in multivariate analysis. The 5-year and 10-year overall survival rates were 89.6% and 81.0%, respectively, and the 5-year and 10-year recurrence-free probabilities were 91.1% and 91.1%, respectively. Eight patients had locoregional recurrence, and 12 had distant recurrence. Multivariate analyses revealed that age more than 70 years (hazard ratio [HR] 2.389), male (HR 2.750), more than 75% consolidation/tumor ratio on high-resolution computed tomography (HR 2.750), and lymphatic permeation (HR 5.618) were independent po...Continue Reading

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Citations

Jul 17, 2013·American Journal of Respiratory and Critical Care Medicine·Charles A PowellSerge P Nana-Sinkam
Dec 10, 2013·World Journal of Surgical Oncology·Hiroaki KomatsuNoritoshi Nishiyama
Jul 23, 2013·The Journal of Thoracic and Cardiovascular Surgery·Terumoto KoikeShin-ichi Toyabe
Jun 27, 2013·Seminars in Thoracic and Cardiovascular Surgery·Jessica S Donington
Nov 7, 2015·The Annals of Thoracic Surgery·Ken KodamaKeiko Kuriyama
Jan 23, 2016·The Annals of Thoracic Surgery·Terumoto KoikeMasanori Tsuchida
May 29, 2012·The Annals of Thoracic Surgery·Pierre-Emmanuel Falcoz
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Sep 25, 2014·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Alan D L Sihoe, Paul Van Schil
Sep 30, 2014·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Mariko KishimotoShinji Naganawa
Jun 15, 2016·General Thoracic and Cardiovascular Surgery·Hisashi Iwata
Nov 13, 2018·Asian Cardiovascular & Thoracic Annals·Constantine Marios SoultanisJiang Lei
Feb 5, 2021·The Thoracic and Cardiovascular Surgeon·Satoshi TakamoriTakanobu Kabasawa

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