PMID: 11319975Apr 26, 2001Paper

Prognostic score of short-term survival in HIV-infected patients admitted to medical intensive care units

International Journal of STD & AIDS
M BonarekC Gabinski

Abstract

A retrospective cohort was set up to identify prognostic factors associated with in-hospital survival in HIV-infected patients admitted to medical intensive care units (MICUs), from 1991 to 1994. Survival from MICU admission to hospital discharge (or in-hospital fatal issue) was estimated and a prognostic score at MICU admission was developed. One hundred and thirty patients were recruited of whom 20% were AIDS-free prior to admission. In-hospital mortality rate was 65%. Median survival was 20 days. The following variables were predictive of mortality: Simplified Acute Physioloy Score II (SAPS II): (hazard ratio [HR]=1.5 for 10 points higher, P<10(-3)), time between HIV diagnosis and admission >5 years (HR=2.7, P<10(-4)), hypoalbuminaemia (HR=1.2 per 5 g/l lower, P=0.03). The prognostic score developed was: SAPS II+25 (if time between HIV diagnosis and MICU admission >5 years) albuminaemia (g/l). A new prognostic score including SAPS II, prior HIV history and albuminaemia better reflected the in-hospital mortality than SAPS II alone. Our findings may still be useful to better evaluate the immediate prognosis of current HIV-infected patients admitted to MICU, particularly those naive to antiretroviral therapy or in treatment fai...Continue Reading

Citations

Oct 11, 2008·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Denise L JacobsonIra B Wilson
Aug 3, 2002·American Journal of Respiratory and Critical Care Medicine·Alison MorrisLaurence Huang
May 5, 2009·Enfermedades infecciosas y microbiología clínica·Pedro M OlaecheaUNKNOWN Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica
Jul 14, 2007·Médecine et maladies infectieuses·A DinhL Bernard
Dec 28, 2004·American Journal of Surgery·Peter H LinAlan B Lumsden
Jan 22, 2010·European Journal of Anaesthesiology·Alberto Corona, Ferdinando Raimondi

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