Prognostic significance of acute presentation with emergency complications of gastric cancer

Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association
Guy R J C BlackshawMiles C Allison

Abstract

Although acute complications necessitating emergency hospital admission are well documented in patients with carcinoma of the colon, comparable data for patients with gastric carcinoma is thin. The aim of this study, therefore, was to examine the outcomes of patients presenting to hospital as acute admissions with emergency complications of previously undiagnosed gastric cancer. Three hundred consecutive patients with gastric adenocarcinoma were studied prospectively, and subdivided into two groups according to whether the patients were referred as acute emergencies ( n = 116) or as outpatients ( n = 184). The commonest emergency complications were: abdominal pain (57%), vomiting (41%), gastrointestinal bleeding (37%), dysphagia (26%), and a palpable mass (18%). Stages of disease were significantly more advanced in patients presenting acutely (I : II : III : IV = 7 : 11 : 27 : 71) compared with patients referred via outpatients (20 : 23 : 50 : 91, Chi(2) = 3.955; DF, 1; P = 0.047). R0 gastrectomy was significantly less likely after acute presentation (23 patients; 20%) compared with patients referred via outpatients (70 patients; 38%; Chi(2) = 11.037; DF, 1; P = 0.001). Cumulative 5-year survival for patients referred acutely w...Continue Reading

Citations

Apr 19, 2013·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Seigo MinamiKiyoshi Komuta
Sep 27, 2012·World Journal of Emergency Surgery : WJES·Peter VasasFrances S Hughes
Feb 27, 2008·World Journal of Gastroenterology : WJG·Giovanni MaconiGabriele-Bianchi Porro
Oct 30, 2012·Journal of Vascular and Interventional Radiology : JVIR·Daniel J TandbergCharles Y Kim
Oct 5, 2010·Gastrointestinal Endoscopy·Stephen J HellerDavid S Weinberg
Nov 24, 2005·Gastroenterology Clinics of North America·Eric Esrailian, Ian M Gralnek
May 15, 2013·Journal of Gastroenterology and Hepatology·Young-Il KimYoung Iee Park
Mar 25, 2014·Journal of Vascular and Interventional Radiology : JVIR·Timothy MeehanSuvranu Ganguli
Jul 5, 2015·Gastrointestinal Endoscopy Clinics of North America·Yen-I Chen, Alan N Barkun
Jan 9, 2015·Annals of Medicine and Surgery·J A YoungA M Thompson
Apr 7, 2015·Clinical Endoscopy·Young-Il Kim, Il Ju Choi
May 14, 2005·The British Journal of Surgery·M R StephensM C Allison
Sep 16, 2019·The Journal of Surgical Research·Benjamin W FisherTania K Arora

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.