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Prognostic significance of cathepsin V (CTSV/CTSL2) in breast ductal carcinoma in situ

Journal of Clinical Pathology

Aug 23, 2019

Michael S TossEmad A Rakha

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Abstract

Cathepsin V (CTSV/CTSL2) is a lysosomal cysteine proteinase and plays a role in extracellular matrix degradation. It is associated with poor prognosis in invasive breast cancer (IBC), but its role in breast ductal carcinoma in situ (DCIS) remains unclear. In this study, we aimed to eval...read more

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Biological Markers
Noninfiltrating Intraductal Carcinoma
Epithelial Cells
Extracellular Matrix
Hormone Receptor
Immunohistochemistry
ErbB-2 Receptor
Evaluation
Comedone
Disease Progression
3
1
3
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Prognostic significance of cathepsin V (CTSV/CTSL2) in breast ductal carcinoma in situ

Journal of Clinical Pathology

Aug 23, 2019

Michael S TossEmad A Rakha

PMID: 31444238

DOI: 10.1136/jclinpath-2019-205939

Abstract

Cathepsin V (CTSV/CTSL2) is a lysosomal cysteine proteinase and plays a role in extracellular matrix degradation. It is associated with poor prognosis in invasive breast cancer (IBC), but its role in breast ductal carcinoma in situ (DCIS) remains unclear. In this study, we aimed to eval...read more

Mentioned in this Paper

Biological Markers
Noninfiltrating Intraductal Carcinoma
Epithelial Cells
Extracellular Matrix
Hormone Receptor
3
1
3

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