Prognostic significance of morphotypes in canine lymphomas: A systematic review of literature

Veterinary and Comparative Oncology
D SayagF Ponce

Abstract

Correlation between morphotypes and prognosis of canine lymphomas presented discordant results in literature, leading to some dilemma for application in clinical practice. The aim of this study was to present a systematic review of literature on the prognostic significance of morphotypes in canine lymphomas. Standardized Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) criteria were applied. Retrospective and prospective studies were included. Level of evidence was determined for each study. Some acceptable evidence suggested a significant prognostic impact of morphotypes in canine lymphomas. However, the evidence is not sufficiently robust to determine with precision the most appropriate classification scheme. Updated Kiel and World Health Organization (WHO) classifications seem to remain the most appropriate classification systems with regards to the number of available studies and their levels of evidence. Limitations included lack of randomized control trial, and relative lack of prospective studies available. Current recommended classification of canine lymphoma is the systematic determination of morphotype in each new case. The Updated Kiel and the WHO classifications adapted to dog both remain ...Continue Reading

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Citations

Mar 2, 2021·Veterinary World·Katarzyna Kliczkowska-KlarowiczRafał A Sapierzyński
Jul 15, 2021·Topics in Companion Animal Medicine·Juliana Silva do NascimentoMaria de Lourdes Gonçalves Ferreira
Nov 28, 2021·Journal of Veterinary Internal Medicine·Valeria MartiniStefano Comazzi

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