Prognostic significance of nodal ratio in cutaneous squamous cell carcinoma of the head and neck.

European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
Aviram MizrachiGideon Bachar

Abstract

The TNM classification is not specific for head and neck skin cancer and makes no allowance for disease extent. Studies have shown that the relative number of metastatic-to-examined lymph nodes, termed the Nodal ratio, is a reliable independent prognosticator in several types of cancer. The study was designed as a retrospective analysis in a university affiliated tertiary care center setting. The files of all patients (n = 71) with cutaneous head and neck squamous cell carcinoma and regional lymph node metastasis who attended a tertiary medical center between 1990 and 2008 were reviewed for clinical variables and outcome, and Nodal ratio was calculated. Data were analyzed for impact on survival. On multivariate analysis Nodal ratio and age were found to be significant predictors of overall survival. The N-ratio was the only significant predictor of disease-specific survival. Age, type of treatment (selective/modified neck dissection), pathologic N stage, and radiotherapy had no effect. The Nodal ratio is a potentially valuable prognostic index in cutaneous squamous cell carcinoma. The minimal number of nodes that need to be excised has to be determined.

References

Jan 1, 1992·International Journal of Radiation Oncology, Biology, Physics·G E LaramoreJ G Schwade
Nov 1, 1986·Archives of Dermatology·A K GuptaH F Haberman
Jan 1, 1970·Cancer·H MartinR H Spiro
Apr 29, 1998·Archives of Otolaryngology--head & Neck Surgery·N Bhattacharyya
Jul 30, 2003·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·T E Le VoyerD G Haller
Nov 13, 2004·Breast Cancer Research : BCR·Vincent Vinh-HungMelanie Royce
Feb 1, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Gary L ClaymanScott M Lippman
Aug 11, 2005·JAMA : the Journal of the American Medical Association·Leslie J ChristensonRandall K Roenigk
Sep 9, 2005·The Laryngoscope·Brian A MooreGary L Clayman
Jun 20, 2006·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Wendy A WoodwardYago Nieto
Aug 5, 2006·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·B Kuru
Apr 7, 2007·Current Opinion in Otolaryngology & Head and Neck Surgery·Carsten E PalmeMichael J Veness
Jun 15, 2007·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·A MarchetUNKNOWN Italian Research Group for Gastric Cancer Study (GIRCG)
Nov 8, 2007·Annals of Surgical Oncology·Carlo Riccardo RossiDonato Nitti
Nov 12, 2009·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Hugo Fontan Köhler, Luiz P Kowalski

❮ Previous
Next ❯

Citations

Jun 20, 2013·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Julian KünzelHeinrich Iro
Mar 8, 2016·Future Oncology·Laura Y Wang, Ian Ganly
May 21, 2014·Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology·Julian KünzelHeinrich Iro
Dec 7, 2013·Head & Neck·Richie Chiu-Lung Chan, Jimmy Yu Wai Chan
Jul 18, 2018·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Misha AmoilsVasu Divi
Jun 26, 2021·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Alberto GrammaticaCesare Piazza
Nov 10, 2021·The Australasian Journal of Dermatology·Nicholas W BucknellAlbert Tiong

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carcinoma, Squamous Cell

Basal cell carcinoma is a form of malignant skin cancer found on the head and neck regions and has low rates of metastasis. Discover the latest research on basal cell carcinoma here.

Related Papers

European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)
Nakul SaxenaHelena M Verkooijen
European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
F J F CoimbraM F S Begnami
© 2021 Meta ULC. All rights reserved