PMID: 25735385Mar 5, 2015Paper

Prognostic significance of preoperative anemia, leukocytosis and thrombocytosis in chinese women with epithelial ovarian cancer

Asian Pacific Journal of Cancer Prevention : APJCP
Ying ChenXiang-Yu Liu

Abstract

Malignant tumors are often accompanied by increased risk of hematological abnormalities. However, few studies have reported any prognostic impact of preoperative thrombocytosis, leukocytosis and anemia in epithelia ovarian cancer (EOC). This study aimed to investigate preoperative hematological parameters for anemia, leukocytosis and thombocytosis in relation to established prognostic factors and survival in EOC cases. A total of 816 Chinese women treated for EOC were retrospectively included in the study focusing on the relationship between preoperative hemoglobin, leukocyte and platelet counts, and a panel of clinicopathologic characteristics and outcome. Preoperative anemia was present in 13.4%, leukocytosis in 16.7% and thrombocytosis in 22.8% . Additionally, EOC patients with low differentiation grade, advanced stage, lymph node (LN) metastasis, residual disease ≥ 1cm, ascites volume >1,000ml, serum cancer antigen 125 (CA125) >675U/ml, and disease recurrence had the higher prevalence of preoperative anemia, leukocytosis and thrombocytosis (all p<0.05). Moreover, EOC patients with older age or postmenopausal EOC patients had the higher prevalence of thrombocytosis (28.7% vs 17.3% or 26.0% vs 17.7%). Furthermore, in a Cox pr...Continue Reading

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Citations

Dec 13, 2017·Climacteric : the Journal of the International Menopause Society·Q ZhouM-Z Zuo
May 26, 2016·Asian Pacific Journal of Cancer Prevention : APJCP·Heru Pradjatmo, Heru Pradjatmo
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Jul 24, 2021·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Ahmed Abu-ZaidIsmail Abdulrahman Al-Badawi

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