Prognostic significance of QRS duration in patients with suspected coronary artery disease referred for noninvasive evaluation of myocardial ischemia

The American Journal of Cardiology
Arend F L SchinkelDon Poldermans

Abstract

The purpose of this study was to evaluate the prognostic significance of QRS duration in patients with suspected coronary artery disease (CAD) referred for noninvasive evaluation of myocardial ischemia by dobutamine stress echocardiography. QRS duration is a prognostic marker in patients with previous myocardial infarction and/or heart failure. The relation between QRS duration and outcome of patients without known heart disease has not been evaluated. A total of 1,227 patients (707 men, mean age 61 +/- 14 years) with suspected CAD underwent dobutamine stress echocardiography for evaluation of myocardial ischemia. Patients were followed to determine predictors of cardiac events and to assess the incremental significance of QRS duration compared to clinical and dobutamine stress echocardiographic data. During a mean follow-up of 4.2 +/- 2.4 years, 280 patients (23%) died (129 cardiac deaths), and 60 (5%) had a nonfatal infarction. Annualized cardiac death rates were 2.0% in patients with QRS duration <120 ms and 4.4% in patients with QRS duration >or=120 ms, respectively (p <0.0001). Annualized event rates for cardiac death/nonfatal infarction were 2.8% in patients with QRS duration <120 ms and 4.8% in patients with QRS duration...Continue Reading

Citations

Oct 6, 2011·Australasian Physical & Engineering Sciences in Medicine·Jinzhong SongRuiyun Zhu
Oct 16, 2010·Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·Shlomo Stern
Oct 31, 2012·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Demosthenes G KatritsisJohn P A Ioannidis
Apr 18, 2018·Journal of Cellular and Molecular Medicine·Chunlian ZhongJun Zou
Aug 16, 2011·Circulation. Arrhythmia and Electrophysiology·Aapo L AroHeikki V Huikuri
Dec 6, 2016·Circulation Journal : Official Journal of the Japanese Circulation Society·Tetsuo YamaguchiMorimasa Takayama
Feb 23, 2021·Frontiers in Physiology·Mira Anette E HaukilahtiHeikki V Huikuri

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