PMID: 9555551Apr 29, 1998Paper

Prognostic significance of seminal vesicle invasion on the radical prostatectomy specimen. Rationale for seminal vesicle biopsies

European Urology
B DebrasG Vallancien

Abstract

The prognostic significance of seminal vesicle invasion on the radical prostatectomy specimen was evaluated according to the proximal or distal site of this invasion. 52 consecutive patients undergoing radical prostatectomy for stage pT3b N0 M0 prostatic cancer were classified into two groups: group A (18 patients): patients with invasion limited to the proximal part of the seminal vesicles (stage T3b limited); group B (34 patients): patients with invasion extending to the free part of the seminal vesicles (stage T3b extensive). The PSA progression-free curves were compared between the two groups. A multivariable regression model was performed to determine independent prognostic factors. Overall, the 5-year PSA progression free rate of the 52 patients was 14.4%. The 5-year PSA progression-free rate of the patients in group A was 45.4 vs. 4.2% at 4 years in group B (p = 0.0004). The stage of seminal vesicle invasion and the Gleason score were the only independent predictive factors of PSA progression (p = 0.02 and p = 0.04, respectively). The prognostic significance of seminal vesicle invasion is not constant and depends on the site of invasion. Preoperative seminal vesicles biopsies can select patients with invasion extending t...Continue Reading

Citations

Jan 16, 2008·Abdominal Imaging·Leo PallweinFerdinand Frauscher
Aug 19, 2007·International Journal of Clinical Oncology·Masakazu TsutsumiHideyuki Akaza
Sep 8, 2010·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Daniel M BerneyUNKNOWN ISUP Prostate Cancer Group
Jun 17, 2016·International Journal of Urology : Official Journal of the Japanese Urological Association·Hyun Jung LeeSung-Woo Park
Apr 11, 2013·Histopathology·Anna KristiansenLars Egevad
Jun 9, 2006·Diagnostic Pathology·A BuhmeidaY Collan
Nov 23, 2006·International Journal of Urology : Official Journal of the Japanese Urological Association·Yuzuri TsurumakiTadaichi Kitamura
Mar 8, 2006·Archives of Pathology & Laboratory Medicine·John R Srigley
Jul 23, 2021·International Journal of Urology : Official Journal of the Japanese Urological Association·Arinobu FukunagaAkiko Miyagi Maeshima
Aug 2, 2021·International Journal of Urology : Official Journal of the Japanese Urological Association·Shinya Yamamoto

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