Prognostic significance of the white coat hypertension in patients with type 1 diabetes mellitus

Diabetes Research and Clinical Practice
L FloresE Esmatjes

Abstract

Despite the high prevalence of white coat hypertension (WCH) in diabetes mellitus and the evidence that hypertension is a clear risk factor for the development of microalbuminuria (MA) in these patients, there is no information on the long-term prognostic significance of this condition in the diabetic population. We studied the evolution of 40 patients with type 1 diabetes mellitus (Type 1 DM). Twenty patients with WCH (office blood pressure> or =140/90mmHg associated with mean daytime blood pressure<135/85mmHg) classified as the WCH group and 20 patients with type 1 DM with a similar age and disease evolution, but who were normotensive, (office blood pressure<140/90mmHg associated with mean daytime blood pressure<135/85mmHg) classified as the normotensive control group. After 5 years of follow-up, MA appeared in four subjects and sustained hypertension in another, with a total of 31% of events in the WCH group, with none in the normotensive group. Kaplan-Meier analysis showed that the relative risk of developing these hypertensive events was 25% higher in the WCH group. At baseline, the night time systolic and diastolic blood pressure levels were significantly higher in patients who further developed MA and sustained hypertens...Continue Reading

References

Sep 1, 1991·Diabetologia·E BurgessZ Josefsberg
Apr 30, 2002·Diabetes·Keith DrummondUNKNOWN International Diabetic Nephropathy Study Group
Sep 13, 2002·The New England Journal of Medicine·Empar LurbeDaniel Batlle
Jun 26, 2003·Journal of Internal Medicine·C E Mogensen

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Citations

Sep 5, 2008·Diabetes Care·Caroline K KramerJorge L Gross
Nov 13, 2009·Diabetes Care·Giuseppe ManciaGuido Grassi
Nov 13, 2009·Diabetes Care·Michael Bursztyn, Iddo Z Ben-Dov
Dec 13, 2012·IEEE Reviews in Biomedical Engineering·Michael C K KhooLimei Cheng
Aug 4, 2007·The Journal of Clinical Hypertension·Kazuo EguchiKazuomi Kario
Oct 18, 2007·Current Opinion in Endocrinology, Diabetes, and Obesity

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