Prognostic significance of vascular and perineural invasion in cancer of the larynx

American Journal of Otolaryngology
T YilmazB Gürsel

Abstract

Perineural and vascular invasion are generally recognized as poor prognostic factors in cancer. The authors report the prognostic significance of perineural and vascular invasion in cancer of the larynx. The laryngectomy specimens of 94 patients with squamous cell carcinoma of the larynx were analyzed histopathologically for vascular and perineural invasion. Prognostic significance of vascular and perineural invasion was evaluated related to the cervical lymph node metastasis, recurrence, and disease-free survival. Vascular invasion significantly influences cervical lymph node metastasis for supraglottic tumors, yet not for glottic and transglottic tumors. Perineural invasion has marginal significance in cases of cervical lymph node metastasis of supraglottic tumors; it has no significance in cases of cervical lymph node metastasis of glottic and transglottic tumors. Vascular invasion significantly increases local and regional recurrence rate, but not distant metastasis rate. Perineural invasion significantly increases local recurrence rate, but not regional recurrence and distant metastasis rate. The disease-free survival is significantly shortened by the presence of vascular and perineural invasion. According to multivariant ...Continue Reading

Citations

Jun 15, 2004·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·O Taskin YücelSefa Kaya
Nov 27, 2007·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Emre VuralJames Y Suen
Jan 10, 2009·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Magdalena ChirilăMihaela Mureşan
Sep 6, 2003·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Taner YilmazBülent Gürsel
Jan 6, 2012·Annals of Oncology : Official Journal of the European Society for Medical Oncology·E FountzilasD Spentzos
Jan 28, 2014·Asian Pacific Journal of Cancer Prevention : APJCP·Aysegul VerimTurgay Isbir
Feb 6, 2017·Surgical Pathology Clinics·Lester D R Thompson
May 4, 2000·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·E VuralE Hanna
Jul 7, 2017·Head & Neck·Kyle T FletcherRony K Aouad
Jun 10, 2005·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Ibrahim ErcanSuat Turgut
Feb 5, 2005·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Taner YilmazErgin Turan
Mar 2, 2005·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Konstantinos VlachtsisIoannis Daniilidis
May 4, 2005·The Laryngoscope·Ronaldo BovaWilliam B Coman
Apr 20, 2010·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Anastasios K GoulioumisHelen Papadaki
Sep 27, 2000·Diseases of the Colon and Rectum·A K SinghT E Read
May 10, 2003·Acta Oto-laryngologica·Ken MacLennanAlessandra Rinaldo
Apr 14, 2016·Oncology Letters·Massimo MesolellaFilippo Ricciardiello
Nov 17, 2019·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Arun GopinathAhmad Alkhasawneh
Feb 18, 2020·Frontiers in Oncology·Ting HuangYudong Wang
Jan 10, 2021·International Journal of Environmental Research and Public Health·Ming-Hsien TsaiChih-Yen Chien
Aug 1, 2012·Annals of Oncology : Official Journal of the European Society for Medical Oncology·E FountzilasD Spentzos
Feb 11, 2000·American Journal of Otolaryngology·G SprianoV Vitale

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