PMID: 16157951Sep 15, 2005Paper

Prognostic value of a qualitative test for heart-type fatty acid-binding protein in patients with acute coronary syndrome

International Heart Journal
Masaru SuzukiKenji Kobayashi

Abstract

Heart-type fatty acid-binding protein (h-FABP) is a novel diagnostic marker for myocardial infarction, but its prognostic value has not been established in patients with acute coronary syndrome (ACS). We sought to determine the value of qualitative analysis of h-FABP for predicting 30-day adverse events in patients with ACS. A retrospective observational study was conducted on patients at a community hospital, and 130 patients admitted through the emergency room (ER) for ACS were identified among 12,077 patients who presented to the ER between January and June 2003. Of these 130 patients, 90 (mean age, 66.8 years, 67 males) who had ACS were eligible for this study. Qualitative tests for serum h-FABP and troponin T (cTnT) were performed on presentation. Follow-up information on adverse events within 30 days after admission, defined as cardiac death or recurrent ACS, was obtained from the medical records. The qualitative tests for h-FABP and troponin T were positive in 62.2% and 36.7%, respectively. The cumulative adverse event rate at 30 days was 14.8% in the h-FABP-positive group and 3.2% in the negative group. The adjusted relative risk of a positive h-FABP test for adverse events was 44.98 (95% CI: 1.48 to 1,364.88). A positi...Continue Reading

References

Oct 31, 1996·The New England Journal of Medicine·E M OhmanE J Topol
Aug 14, 2001·Journal of the American College of Cardiology·P A HeidenreichM A Hlatky
Mar 19, 2004·QJM : Monthly Journal of the Association of Physicians·H A Alhadi, K A A Fox

❮ Previous
Next ❯

Citations

Sep 18, 2009·Intensive Care Medicine·Natacha TurckJean-Charles Sanchez
Feb 9, 2016·Journal of Forensic and Legal Medicine·Çağlar Özdemirİbrahim İkizceli
Dec 18, 2008·Journal of Thrombosis and Haemostasis : JTH·N VuilleumierM Righini
Nov 21, 2007·Journal of the American College of Cardiology·James A de Lemos, Michelle O'Donoghue
Nov 16, 2010·Human & Experimental Toxicology·Ayça AçikalinOnur Akpinar
Sep 21, 2013·Biomarker Insights·Antoine KossaifyUNKNOWN STAR-P Consortium
Jan 1, 2008·Biomarker Insights·Valentina LoriaLuigi M Biasucci
Jul 23, 2020·Annals of Medicine·Harsh GoelGregory Y H Lip
Feb 23, 2021·Frontiers in Cardiovascular Medicine·Yuling WuLijuan Zhang

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.