PMID: 26320475Sep 1, 2015Paper

Prognostic Value of Baseline Neutrophil-Lymphocyte and Platelet-Lymphocyte Ratios in Local and Advanced Gastric Cancer Patients

Asian Pacific Journal of Cancer Prevention : APJCP
Mehmet Naci AldemirSalim Basol Tekin

Abstract

We aimed to investigate the prognostic value of baseline neutrophil, lymphocyte, and platelet counts along with the neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) in local and advanced gastric cancer patients. In this retrospective cross-sectional study, a total of 103 patients with gastric cancer were included. For all, patient characteristics and overall survival (OS) times were evaluated. Data from a complete blood count test including neutrophil, lymphocyte, monocyte, white blood cell (WBC) and platelet (Plt) count, hemoglobin level (Hb) were recorded, and the NLR and PLR were obtained for every patient prior to pathological diagnosis before any treatment was applied. Of the patients, 53 had local disease, underwent surgery and were administered adjuvant chemoradiotherapy where indicated. The remaining 50 had advanced disease and only received chemotherapy. OS time was 71.6±6 months in local gastric cancer patients group and 15±2 months in the advanced gastric cancer group. Univariate analysis demonstrated that only high platelet count (p=0.013) was associated with better OS in the local gastric cancer patients. In contrast, both low NLR (p=0.029) and low PLR (p=0.012) were associated with better OS i...Continue Reading

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Citations

Mar 5, 2016·Cancer Investigation·Zhihao ZhangXiaoyan Zhao
Aug 10, 2016·Journal of Medical Microbiology·Sevki Hakan ErenMustafa Gökhan Gözel
May 15, 2018·The American Journal of Chinese Medicine·Huiying FuQiyang Shou
Oct 17, 2019·Revista da Associação Médica Brasileira·Emrah Erdal, Mehmet İnanir
Sep 14, 2017·Chinese Journal of Cancer·Kang WangJianhui Chen
Mar 16, 2017·Open Access Macedonian Journal of Medical Sciences·Caner Sahin, Ceyhun Varım

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