Abstract
We analysed the prognostic value of somatosensory, brainstem auditory and visual evoked potentials (SSEPs, BAEPs and VEPs, respectively) for outcome prediction in cardiac arrest patients with targeted temperature management (TTM) and assessed whether BAEP and VEP measurements conferred added value to SSEP measurements. Cases with SSEPs and VEPs or BAEPs were reviewed in a TTM registry. We focused on whether the following responses were clearly discernible: N20 for SSEPs, V for BAEPs, and P100 for VEPs. Each type of evoked potential was classified as absent, present or indeterminable. Neurological outcomes after 6 months were dichotomized as good (Cerebral Performance Category [CPC] 1-2) or poor (CPC 3-5). From 185 patients, 185 SSEPs, 172 BAEPs and 178 VEPs were included. None of the patients with a good outcome had absent SSEP, BAEP or VEP responses. Absent SSEP, BAEP and VEP responses yielded sensitivities of 42.3% (95% confidence interval [CI], 33.7-51.3%), 9.4% (95% CI, 4.6-16.7%) and 54.4% (95% CI, 46.0-62.5%) for poor outcomes, respectively. For the overall cohort, the addition of VEP measurements improved the sensitivities of single SSEP measurements (65.8% [95% CI, 57.7-73.3%] versus 36.2% [95% CI, 28.6-44.4%] and multi...Continue Reading
References
Oct 1, 1986·Electroencephalography and Clinical Neurophysiology·H SohmerK Goitein
May 1, 1993·Neurophysiologie clinique = Clinical neurophysiology·J M GuéritP Mahieu
Jul 29, 1998·Electroencephalography and Clinical Neurophysiology·J M Guérit
Aug 13, 2005·Critical Care Medicine·Marjaana TiainenRisto O Roine
Sep 28, 2005·Progress in Brain Research·Jean-Michel Guérit
Jun 21, 2006·Resuscitation·Atsushi SakuraiKatsuhisa Tanjoh
May 27, 2009·Neurophysiologie clinique = Clinical neurophysiology·J-M GuéritY Péréon
Feb 16, 2010·Critical Care : the Official Journal of the Critical Care Forum·Seung Pill ChoiHyeon Woo Yim
Jul 10, 2013·Neurocritical Care·Michael HuntgeburthHannes Reuter
Jul 23, 2013·Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine·Soo Hyun KimSe Min Choi
Feb 11, 2014·Sleep Medicine·Stefano de BiaseMariarosaria Valente
Dec 2, 2014·Resuscitation·Claudio SandroniJasmeet Soar
Oct 17, 2015·Circulation·Clifton W CallawayJanice L Zimmerman
Oct 20, 2015·Resuscitation·Jerry P NolanClaudio Sandroni
Oct 19, 2016·Clinical and Experimental Emergency Medicine·Young-Min KimSung Oh Hwang
Feb 2, 2017·Seminars in Neurology·Janneke Horn, Marleen C Tjepkema-Cloostermans
Feb 2, 2017·Seminars in Neurology·Tobias Cronberg, Michael Kuiper
Jun 27, 2017·Resuscitation·Seung Pill ChoiJoo Suk Oh
Jul 21, 2017·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Aldo RagazzoniSimone Rossi
Sep 25, 2017·Resuscitation·Paolo De SantisFabio Silvio Taccone
May 23, 2018·Neurophysiologie clinique = Clinical neurophysiology·Nathalie André-ObadiaArnaud Delval
Jun 4, 2019·Annals of Neurology·Barry J RuijterJeannette Hofmeijer
Jun 20, 2019·Critical Care : the Official Journal of the Critical Care Forum·Sang Hoon OhSeong Hoon Kim
Jul 12, 2019·Circulation·Romergryko G GeocadinUNKNOWN American Heart Association Emergency Cardiovascular Care Committee
Oct 28, 2019·Critical Care : the Official Journal of the Critical Care Forum·Ted L Rothstein
Dec 4, 2019·Resuscitation·Maenia ScarpinoUNKNOWN ProNeCA study group
Mar 15, 2020·Resuscitation·Sang Hoon OhUNKNOWN KORHN investigators
Jun 23, 2020·Critical Care Medicine·Sang Hoon OhUNKNOWN Cerebral Resuscitation and Outcome Evaluation Within Catholic Network (CROWN) Investigators
Sep 12, 2020·Intensive Care Medicine·Claudio SandroniTobias Cronberg
Sep 27, 2020·Handbook of Clinical Neurology·Marie P Pittet-MetraillerEmily W Y Tam