Prognostic value of calcium score and coronary flow velocity reserve in asymptomatic diabetic patients

Cardiovascular Ultrasound
Miodrag DikicAleksandra Arandjelovic

Abstract

The risk stratification of patients with diabetes mellitus (DM) is a major objective for the clinicians, and it can be achieved by coronary flow velocity reserve (CFVR) or with coronary artery calcium score (CS). CS evaluates underlying coronary atherosclerotic plaque burden and CFVR estimates both presence of coronary artery stenosis and microvascular function. Consequently, CFVR may provide unique risk information beyond the extent of coronary atherosclerosis. Our aim is to assess joint prognostic value of CFVR and CS in asymptomatic DM patients. We prospectively included 200 asymptomatic patients (45,5 % male, mean age 57,35 ± 11,25), out of which, there were 101 asymptomatic patients with DM and 99 asymptomatic patients without DM, but with one or more conventionally risk factors for coronary artery disease. We analyzed clinical, biochemical, metabolic, inflammatory parameters, CS by Agatston method, transthoracic Doppler echocardiography CFVR of left anterior descending artery and echocardiographic parameters. Total CS and CS LAD were significantly higher, while mean CFVR was lower in diabetics compared to the nondiabetics. During 1 year follow-up, 24 patients experienced cardio-vascular events (one cardiovascular death, t...Continue Reading

References

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Citations

Apr 9, 2016·JACC. Cardiovascular Imaging·Lauren A BaldassarreUNKNOWN American College of Cardiology’s Cardiovascular Disease in Women Committee
Aug 18, 2017·European Journal of Nuclear Medicine and Molecular Imaging·Roberta AssanteAlberto Cuocolo
Dec 15, 2019·European Journal of Nuclear Medicine and Molecular Imaging·Emilia ZampellaAlberto Cuocolo

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Methods Mentioned

BETA
coronary bypass

Software Mentioned

SPSS

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