PMID: 15373990Sep 18, 2004Paper

Prognostic value of Charlson comorbidity index at 30 days and 1 year after acute myocardial infarction

Revista española de cardiología
Julio E NúñezFrancisco J Chorro

Abstract

The Charlson comorbidity index (CCI), an indicator of comorbidity, has been used as an adjusting variable in multivariate models. Because of its prognostic value per se for cardiovascular complications after acute myocardial infarction (AMI), we sought to determine the predictive value of the CCI for all-cause mortality and recurrent AMI 30 days and 1 year after the index event. We analyzed 1035 consecutive patients admitted with the diagnosis of AMI (ST elevation=508 and non-ST elevation=527). The composite endpoint was determined after 30 days (13.9%) and 1 year (26.3%) of follow-up. The CCI was calculated on admission, and other variables with prognostic value were also recorded. CCI was stratified in 4 categories: 1: CCI=0 (control), 2: CCI=1, 3: CCI=2,4: CCI> or =3. Cox proportional risks analysis was used for the multivariate analysis, and the C-statistic was calculated to assess the discriminative power of the models. Hazard ratios (95% CI) estimated for each category of CCI were: 2=1.69 (1.10-2.59), 3=1.78 (1.08-2.92) and 4=1.57 (0.87-2.83) at 30 days; 2=1.62 (1.18-2.23), 3=2.00 (1.39-2.89) and 4=2.24 (1.50-3.36) at 1 year. Comparisons with the C-statistic between the nested multivariate models (with and without CCI) yi...Continue Reading

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Citations

Jul 17, 2007·BMC Health Services Research·María J Aguado-RomeoUNKNOWN Medical Practice Variations Andalusian Group
Nov 2, 2013·Journal of the American Medical Informatics Association : JAMIA·Hojjat SalmasianCarol Friedman
May 18, 2016·American Heart Journal·Sean van DiepenJustin A Ezekowitz
Jan 17, 2012·The American Journal of Cardiology·Zefeng ZhangPaula W Yoon
Sep 12, 2006·European Journal of Internal Medicine·F J Gonzalez BarcalaL Valdes Cuadrado
May 12, 2016·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Lorenzo FalsettiFrancesco Pellegrini
Oct 2, 2008·JPEN. Journal of Parenteral and Enteral Nutrition·David Isaac GainesMark H DeLegge
Feb 27, 2020·Journal of the American Heart Association·Basile MouhatUNKNOWN Observatoire des Infarctus de Côte d'Or Survey

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