Prognostic value of dobutamine stress echocardiography in patients with systemic hypertension and known or suspected coronary artery disease

The American Journal of Cardiology
Fabiola B SozziDon Poldermans

Abstract

Currently, there are no outcome data to suggest an incremental value of stress echocardiography in the risk stratification of patients who have hypertension after controlling for the left ventricular mass index (LVMI). This study assessed the incremental value of dobutamine stress echocardiography (DSE) for the prediction of mortality rate and cardiac events in patients who have hypertension. We studied 596 patients who had hypertension (mean age 62 +/- 12 years; 382 men) and who underwent DSE for evaluation of known or suspected coronary artery disease. End points during follow-up were hard cardiac events (cardiac death and nonfatal myocardial infarction) and total mortality rate. Left ventricular hypertrophy was detected by echocardiography in 119 patients (20%). During a median follow-up of 3 years, 101 patients (17%) died (43 cardiac deaths) and 19 patients had nonfatal myocardial infarction. In an incremental multivariate analysis model, clinical predictors of hard cardiac events were age, history of congestive heart failure, and LVMI. The percentage of abnormal myocardial segments examined with DSE was incremental to the clinical model (chi square 41 vs 27, p <0.001). Clinical predictors of total mortality rate were age, ...Continue Reading

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Citations

Oct 7, 2009·Future Cardiology·Riccardo RambaldiCesare Fiorentini
Dec 6, 2005·Cardiology Clinics·Dick KuoCharles S White
Feb 20, 2007·American Heart Journal·Sébastien BergeronPatricia A Pellikka
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Aug 12, 2005·Current Opinion in Cardiology·Elena BiaginiDon Poldermans
Mar 23, 2017·Cardiovascular Ultrasound·Rosa Sicari, Lauro Cortigiani

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