Prognostic value of echocardiographic calcium score in patients with a clinical indication for stress echocardiography

JACC. Cardiovascular Imaging
Nicola GaibazziPompilio Faggiano

Abstract

The value of the echocardiographic calcium score (eCS) was evaluated to predict cardiac events in a multicenter cohort of subjects without known coronary disease, who underwent stress echocardiography (SE) for suspected coronary artery disease (CAD). Several studies have established that aortic valve sclerosis and/or calcification and mitral calcification, as detected by echocardiography, predict cardiovascular morbidity and mortality. The use of a semiquantitative total cardiac calcium score (eCS) to assess aortic and mitral valves, papillary muscles, and the ascending aorta has never been tested in multicenter studies; the inherent subjectivity and clinical applicability of such a parameter remains a concern. We identified 1,303 patients from 5 Italian institutions and 1 U.S. institution, who had no known CAD and who underwent clinically-indicated pharmacological or exercise SE. They were followed up for myocardial infarction (MI) and all-cause death. eCS was assessed from archived images, and its discrimination and reclassification prognostic potential was determined. Fifty-eight patients met the combined endpoint of all-cause death (n = 37; 2.8%) or MI (n = 21; 1.6%) during a median follow-up of 808 days. Age, diabetes mell...Continue Reading

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Citations

Jul 3, 2015·Circulation Journal : Official Journal of the Japanese Circulation Society·Kazuhiro YamamotoTohru Masuyama
Jan 12, 2016·Revista Española De Cardiología·Teresa López-FernándezJoaquín Barba-Cosials
Apr 18, 2015·JACC. Cardiovascular Imaging·Julius M Gardin
Oct 16, 2016·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Marvin Louis Roy LuGregg S Pressman
Oct 30, 2016·European Journal of Preventive Cardiology·Giovanni CioffiMaurizio Rossini
Aug 8, 2018·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Kristof HirschbergHugo A Katus
Mar 9, 2019·European Journal of Preventive Cardiology·Pompilio FaggianoGregg Pressman
Oct 12, 2020·The International Journal of Cardiovascular Imaging·Olena NemchynaJan Knierim
Mar 12, 2021·Echocardiography·Andrea RossiPompilio Faggiano
Dec 29, 2020·Nefrología : publicación oficial de la Sociedad Española Nefrologia·Lidia Martínez FernándezAngels Betriu
Apr 20, 2021·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Tony Y W LiChing-Hui Sia

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