Prognostic Value of Hepatorenal Function By Modified Model for End-stage Liver Disease (MELD) Score in Patients Undergoing Tricuspid Annuloplasty

Journal of the American Heart Association
Yan ChenKai-Hang Yiu

Abstract

The Model for End-stage Liver Disease excluding international normalized ratio (MELD-XI) score and the modified MELD score with albumin replacing international normalized ratio (MELD-Albumin) score, which reflect both liver and renal function, have been reported as predictors of adverse events in liver and heart disease. Nonetheless, their prognostic value in patients undergoing tricuspid annuloplasty has not been addressed. A total of 394 patients who underwent tricuspid annuloplasty were evaluated. Baseline clinical, laboratory, and echocardiographic parameters were recorded. Adverse outcome was defined as the occurrence of heart failure requiring admission or all-cause mortality. Patients who underwent tricuspid annuloplasty had a high prevalence of preoperative hepatorenal dysfunction that was more common in patients with severe tricuspid regurgitation than those with mild to moderate tricuspid regurgitation. The MELD-XI and MELD-Albumin scores were excellent predictors of 1-year adverse outcome (area under the curve: 0.69 and 0.75, respectively). Kaplan-Meier survival curve demonstrated that a high score on MELD-XI (≥12.0) and MELD-Albumin (≥10.7) was associated with an increased risk of adverse events. During a median fol...Continue Reading

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Citations

Apr 28, 2020·Journal of Cardiac Surgery·Brian AyersIgor Gosev
Jan 26, 2021·Frontiers in Cardiovascular Medicine·Masood Abu-HalimaTanja Raedle-Hurst
Mar 27, 2021·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Bettina PfannmuellerMichael A Borger
Apr 8, 2021·European Heart Journal Cardiovascular Imaging·Yan ChenKai-Hang Yiu
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Jun 15, 2021·Journal of Cardiac Surgery·Liang YangHuan-Lei Huang
Jun 18, 2021·Journal of Cardiac Surgery·Kevin LimRandolph Hung Leung Wong
Jul 14, 2021·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Tetsu TanakaMarc Ulrich Becher
Dec 15, 2020·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Satoshi WatanabeAnkit Bharat
Apr 9, 2021·The Journal of Cardiovascular Surgery·Bettina PfannmuellerMichael A Borger

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Methods Mentioned

BETA
coronary artery bypass

Software Mentioned

SPSS
Stata

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