PMID: 1195475Dec 1, 1975Paper

Prognostic value of host immunocompetence in urologic cancer patients

The Journal of Urology
W J CatalonaJ I Harty

Abstract

To evaluate the prognostic significance of host immunocompetence in urologic cancer patients, the subsequent clinical course of 95 patients was determined a year after skin testing with dinitrochlorobenzene. A close correlation was demonstrated between dinitrochlorobenzene reactivity and prognosis among 38 transitional carcinoma patients. Of 19 patients with impaired reactivity 13 had tumor recurrences and 11 of these died of cancer within 1 year. Only 5 of 19 patients with normal dinitrochlorobenzene reactivity had recurrences and none died during the same interval. Although not statistically significant, similar results were observed among 10 renal cell carcinoma patients of whom 3 of 5 with impaired dinitrochlorobenzene reactivity had tumor recurrences, while 4 of 5 with normal reactivity remained free of tumor. One testis tumor patient with impaired dinitrochlorobenzene reactivity died of cancer, while 3 of 4 with normal reactivity remained free of tumor. Similarly, 1 patient with carcinoma of the penis with impaired dinitrochlorobenzene reactivity died of cancer, while 2 of 3 with normal reactivity remained free of tumor. In contrast, reactivity to dinitrochlorobenzene did not correlate with the clinical course of 38 prost...Continue Reading

References

Feb 1, 1974·The Journal of Urology·A P McLaughlinR F Gittes
Dec 1, 1974·The Journal of Urology·W J Catalona
Jan 1, 1974·Plastic and Reconstructive Surgery·M A Mandel, C L Kiehn
Feb 1, 1974·The Journal of Urology·W J CatalonaE E Trahan
Apr 1, 1972·The Journal of Urology·C A OlssonW E Byrd
Dec 1, 1971·British Journal of Urology·M R RobinsonR H Whitaker

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Citations

Jan 1, 1980·The Prostate·J S ElderL M Nyberg
Jul 1, 1977·The Journal of Urology·W J Catalona
Jan 1, 1980·Journal of Surgical Oncology·P GuinanG Baumgartner
Jan 1, 1978·The Journal of Urology·W J Catalona, W W Scott
Feb 1, 1979·The Journal of Urology·S BrosmanJ Fahey
Oct 1, 1978·The Journal of Urology·S S StefaniS S Clark
Jul 1, 1991·The Journal of Urology·T J KinahanA D Manson

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