Prognostic value of normal exercise 99mTc-sestamibi myocardial tomography in patients with angiographic coronary artery disease

Nuclear Medicine Communications
Min-Fu YangZuo-Xiang He

Abstract

Previous studies have documented the prognostic value of normal exercise Tl myocardial perfusion imaging in patients with angiographic coronary artery disease (CAD). However, data on exercise Tc-sestamibi myocardial single photon emission computed tomography (SPECT) are scant. Accordingly, the purpose of this study was to investigate the prognostic value of normal exercise Tc-sestamibi SPECT in patients with angiographic CAD. We retrospectively investigated 90 consecutive patients who had a normal exercise Tc-sestamibi myocardial SPECT but angiographic CAD. A group of 69 consecutive patients with both normal exercise Tc-sestamibi myocardial SPECT and coronary arteries were included as control. During a mean follow-up of 50+/-19 months, a total of three hard cardiac events (non-fatal myocardial infarction) and seven soft cardiac events (late revascularization) were observed. The annual hard cardiac event rate between the two groups was not significantly different (0.6% vs. 0.3%, chi=0.47, P=NS), nevertheless the annual soft cardiac event rate was higher in patients with angiographic CAD (1.9% vs. 0, chi=5.74, P=0.02). Moreover, the annual hard cardiac events rate in patients with angiographic CAD who were treated medically was a...Continue Reading

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Citations

Nov 10, 2010·European Journal of Nuclear Medicine and Molecular Imaging·Manjola DonaRoberto Sciagrà
Aug 2, 2012·International Journal of Radiation Biology·Marcia de Oliveira PereiraMario Bernardo-Filho
Jul 17, 2007·Journal of the American College of Cardiology·Daniel M Spevack, Jeffrey M Levsky

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