Prognostic Value of Right Ventricular Two-Dimensional and Three-Dimensional Speckle-Tracking Strain in Pulmonary Arterial Hypertension: Superiority of Longitudinal Strain over Circumferential and Radial Strain.

Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography
Yuman LiMingxing Xie

Abstract

Right ventricular (RV) dysfunction is a predictor of adverse outcomes in patients with pulmonary arterial hypertension (PAH). Three-dimensional (3D) speckle-tracking echocardiography (STE) has been increasingly used to quantify RV function. However, the strain parameters evaluated by two-dimensional (2D) STE and 3D STE, which provide the most valuable clinical information, remain unknown. The purpose of our study was to investigate whether RV longitudinal strain (LS) provided a superior estimation of RV systolic performance and prognostic information compared with other strain vectors. We prospectively studied 54 treatment-naïve patients with PAH and 35 normal controls. Pulmonary artery systolic pressure classified patients with PAH into three subgroups. Patients with PAH underwent echocardiography, cardiac magnetic resonance (CMR) imaging, 6-minute walking tests, and right-sided cardiac catheterization before and six months after vasodilator therapy. The 2D LS, 3D LS, circumferential strain (CS), and radial strain (RS) of RV free wall were calculated by 2D and 3D STE. RV ejection fraction (RVEF) was obtained from CMR. The patients were followed for a predefined endpoint of PAH-related hospitalization and death. Our findings re...Continue Reading

Citations

Jan 1, 2021·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Yuman LiMingxing Xie
Feb 5, 2021·Frontiers in Cardiovascular Medicine·Yuji XieLi Zhang
Jul 3, 2021·Journal of Clinical Medicine·Ioannis T FarmakisGeorge Giannakoulas
Jul 20, 2021·Frontiers in Cardiovascular Medicine·Yuanli MengMingxing Xie
Jul 24, 2021·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Hongxia NingTan Li
Aug 8, 2021·Journal of Clinical Medicine·Weronika Topyła-PutowskaAndrzej Tomaszewski
Nov 19, 2021·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Marius KellerHarry Magunia

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