Prognostic value of sCD14-ST (presepsin) in cardiac surgery

Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery
D A PopovMikhail Yaroustovsky

Abstract

Prediction of complications and mortality after cardiac surgery is an important aspect of timely correction of these conditions. One possibility in this case is the use of biomarkers and some prognostic scores. To study the prognostic value of presepsin (PSP) as a predictor of postoperative complications development in cardiosurgical patients. Patients operated for acquired heart diseases with cardiopulmonary bypass (CPB) were included in the study (n = 51, age: 58 ± 11 years). Besides routine clinical and laboratory data, PSP and procalcitonin (PCT) levels were monitored perioperatively (before surgery, and on the 1(st), 2(nd), 3(rd) and 6(th) day after surgery). There were no clinical signs of infection before surgery in any of the studied patients. We found supranormal PSP levels in 6 patients (11.8%) before operations (543 [519-602] pg/ml, max 1597 pg/ml; normal value: 365 pg/ml). Infectious complications developed in 19 patients (37%). Statistically significant differences in PSP levels, APACHE II (Acute Physiology and Chronic Health Evaluation II) and SOFA (Sequential Organ Failure Assessment) scores in groups of patients with and without infection were documented from the 1(st) and in PCT from the 2(nd) day after the ope...Continue Reading

Citations

Feb 19, 2020·Minerva anestesiologica·Jessica HandkeEdoardo De Robertis
Jan 19, 2017·Anesthesiology·Hagen BombergHeinrich Volker Groesdonk
Mar 30, 2018·International Journal of Hypertension·Ismail BiyikFaruk Akturk

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Methods Mentioned

BETA
coronary artery bypass

Software Mentioned

SPSS
Statistica

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