PMID: 11605786Oct 19, 2001Paper

Prognostic value of the acute DMSA scan in children with first urinary tract infection

Pediatric Nephrology : Journal of the International Pediatric Nephrology Association
A BiggiG Camuzzini

Abstract

We attempted to verify in a group of 101 children with first urinary tract infection whether it was possible to identify groups of patients with different risks of developing renal scarring by taking into account both the extent of kidney involvement documented in the acute phase of infection using a dimercaptosuccinic acid (DMSA) scan, and the presence or absence of vesicoureteral reflux (VUR). The frequency of persistent lesions in kidneys with mild-moderate lesions (less than 50% of kidney involvement) in the presence of VUR or in non-refluxing kidneys was similar (P=0.1447), while the frequency of persistent lesions in kidneys with severe lesions in the presence of VUR was significantly higher than the frequency of persistent lesions in non-refluxing kidneys (P=0.0089). The extent of kidney involvement and the presence of VUR make possible the identification of different categories of risk of scarring: in the "low risk group" (normal kidney with/without VUR) the risk of scarring is 0%; in the "intermediate risk group" (mild lesions with/without VUR; extensive lesions without VUR) the risk of scarring is between 14% and 38%, while in the "high risk group" (extensive lesions with VUR) the risk of scarring is 88%. Quantifying ...Continue Reading

Citations

Jun 24, 2005·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Mohamed ZakiMoodambaill Adul Rahman
Aug 6, 2005·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Neamatollah AtaeiMosa Khorasani
Mar 18, 2010·The Pediatric Infectious Disease Journal·Chi-Hui ChengTzou-Yien Lin
Mar 3, 2009·Nuclear Medicine Communications·Marianne C TondeurHamphrey H Ham
Nov 21, 2007·Current Opinion in Pediatrics·Ron Keren
Jan 15, 2008·International Journal of Antimicrobial Agents·Barbara G PiccoliMauro Frascisco
Jul 21, 2006·International Journal of Antimicrobial Agents·Giorgina B PiccoliG Piccoli
Jul 6, 2016·The Cochrane Database of Systematic Reviews·Nader ShaikhStephanie W Hum
Apr 18, 2003·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Kuang-Yen LinYuan-Yow Chiou

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