Prognostic value of the interpectoral lymph nodes in breast cancer. A 20-year survival study.

Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
A García-Vilanova ComasM García-Vilanova Comas

Abstract

The indication and extent of axillary lymph node dissection in breast cancer remains open to controversy. In this context, a 20-year survival study has been made of 1600 breast cancer patients subjected during surgical treatment to systematic dissection of the acromiothoracic vascular pedicle together with the accompanying lymph nodes (Rotter and Grossman interpectoral lymph node groups). An anatomical study of these nodes was also conducted in 100 necropsies, with the evaluation of 200 acromiothoracic vascular pedicles. The interpectoral lymph nodes were anatomically present in 42% of the necropsies and in 35.1% of the patients subjected to surgery. The prognosis was much worse in cases of neoplastic infiltration of the interpectoral lymph nodes (Kaplan-Meier survival study), regardless of the influence of other prognostic factors. In view of the results obtained, the designation of grade N3 of the TNM classification is proposed for malignancies with positive interpectoral lymph node infiltration.

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May 11, 2010·Breast Cancer Research and Treatment·Tobias M WeissenbacherDarius Dian
Dec 11, 2007·Nucleosides, Nucleotides & Nucleic Acids·Gabriela IvanovaChristian Leumann
Dec 6, 2007·The Journal of Infectious Diseases·Allison GrosethHeinz Feldmann

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