Prognostic value of tissue Doppler right ventricular systolic and diastolic function indexes combined with plasma B-type natriuretic Peptide in patients with advanced heart failure secondary to ischemic or idiopathic dilated cardiomyopathy

The American Journal of Cardiology
Vasiliki BistolaDimitrios T Kremastinos

Abstract

Right ventricular (RV) dysfunction adversely affects prognosis in patients with chronic heart failure (CHF) due to left ventricular (LV) dysfunction. However, little evidence exists regarding the prognostic role of RV systolic and diastolic function indexes in combination with plasma B-type natriuretic peptide (BNP) in advanced CHF. Thus, 102 consecutive hospitalized patients with advanced CHF (New York Heart Association classes III to IV) due to LV systolic dysfunction (LV ejection fraction <35%) were studied by 2-dimensional conventional and tissue Doppler imaging (TDI) echocardiography of the left and right ventricles. Plasma BNP was also measured. Patients were followed for 6 months for major cardiovascular events (cardiovascular death and/or CHF-related hospitalization). During follow-up, 13 patients died and 63 patients reached the combined end point of cardiovascular death or CHF-related hospitalization. By univariate analysis, RV TDI systolic velocity, dilated cardiomyopathy, digoxin treatment (all p values <0.01), and female gender (p <0.05) were associated with increased cardiovascular death. Transmitral Doppler to mitral annular TDI early diastolic velocity ratio, RV TDI early diastolic velocity (p <0.05), and ratio ...Continue Reading

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Citations

Feb 18, 2016·European Journal of Internal Medicine·Yuichiro MinamiUNKNOWN ATTEND Study Investigators
Nov 16, 2013·The American Journal of Cardiology·Gherardo FinocchiaroEuan A Ashley
Jun 22, 2016·Clinical Physiology and Functional Imaging·José Francisco Forteza-AlbertíFrancisco Javier Calderón-Montero
Jul 28, 2011·Congestive Heart Failure·Andreas P KalogeropoulosVasiliki V Georgiopoulou
Apr 2, 2016·Archives of Cardiovascular Diseases·Pascal de Groote
Nov 6, 2013·TheScientificWorldJournal·Alberto PalazzuoliRanuccio Nuti
Jan 22, 2019·Circulation Journal : Official Journal of the Japanese Circulation Society·Mohamed RadyKrunoslav Michael Sveric
Feb 13, 2013·Nature Reviews. Cardiology·Marc A Simon

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