PMID: 3747593Apr 1, 1986Paper

Prognostic variables in late follow-up of aortic valve replacement using the proportional hazard model: a study on patients using the Medtronic-Hall cardiac prosthesis

Life Support Systems : the Journal of the European Society for Artificial Organs
M AbdelnoorK V Hall

Abstract

An alternative approach to the study of the follow-up of patients with heart prostheses is the use of the reliability theory (hazard function) and proportional hazard model (Cox's model). In a population of 480 patients who underwent AVR in the period from June 1977 to January 1983, with a mean follow-up time of 2.8 years, 16 preoperative variables were considered. From this pool of variables, six entered the regression model in a time-independent mode. These were age at operation, sex, preoperative NYHA classification, presence of AI, presence of endocarditis and presence of atrial fibrillation on ECG, none of which entered the model in the time-related mode. Another multifactorial approach, using a stepwise regression analysis to examine primary predictive factors that independently correlate with survival, while simultaneously accounting for the other previous variables, showed that the variables with additive prognostic value were age at operation, presence of AI and presence of endocarditis. Based on this model, a forecast five-year survival rate ranging from 88 to 14 per cent was found at the end of the fifth year. For the most favourable and the worst combinations of these prognostic variables, a patient-specific forecas...Continue Reading

Related Concepts

Related Feeds

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.

Atrial Filbrillation

Atrial fibrillation refers to the abnormal heart rhythm characterized by rapid and irregular beating of the atria. Here is the latest research.

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.

Related Papers

Scandinavian Journal of Thoracic and Cardiovascular Surgery
M AbdelnoorE Ovrum
Scandinavian Journal of Thoracic and Cardiovascular Surgery
M AbdelnoorE Ovrum
European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
A TsuchiyaR Abe
© 2021 Meta ULC. All rights reserved