Abstract
(i) In 2015-2017 we compared possible reasons for longevity of two mammalian highly social species, i.e. naked mole rats and humans. We proposed that in both cases longevity is a result of neoteny, prolongation of youth by deceleration of late ontogeny (Skulachev, V. P. (2015) Abst. 11th Conf. on Mitochondrial Physiology (MiP2015), Lucni Bouda, Czech Republic, pp. 64-66; Skulachev, V. P., Holtze, S., Vyssokikh, M. Y., Bakeeva, L. E., Skulachev, M. V., Markov, A. V., Hildebrandt, T. B., and Sadovnichii, V. A. (2017) Physiol. Rev., 97, 699-720). Both naked mole rats and humans strongly decreased the pressure of natural selection, although in two different manners. Naked mole rats preferred an "aristocratic" pathway when reproduction (and, hence, involvement in evolution) is monopolized by the queen and her several husbands. Huge number of subordinates who have no right to take part in reproduction and hence in evolution serves the small queen's family. Humans used an alternative, "democratic" pathway, namely technical progress facilitating adaptation to the changing environmental conditions. This pathway is open to all humankind. (ii) As a result, aging as a mechanism increasing evolvability by means of facilitation of natural se...Continue Reading
References
Sep 1, 1978·Mechanisms of Ageing and Development·V M Dilman
Feb 1, 1975·Journal of Neurochemistry·T E DuffyR C Vannucci
Sep 1, 1975·Journal of Theoretical Biology·A Zahavi
Jan 1, 1976·Biology of the Neonate·G C Randall, C L'Ecuyer
Jan 1, 1986·Journal of Pineal Research·R L SackC M Singer
Aug 1, 1972·British Journal of Cancer·J F KerrA R Currie
Feb 1, 1980·General and Comparative Endocrinology·A J BradleyA K Lee
Dec 1, 1993·Free Radical Biology & Medicine·H H KuR S Sohal
Nov 1, 1993·The American Journal of Clinical Nutrition·W L Dills
May 1, 1996·Quarterly Reviews of Biophysics·V P Skulachev
Nov 22, 1997·FEBS Letters·S S KorshunovA A Starkov
May 22, 1998·General Pharmacology·B Klosterhalfen, R S Bhardwaj
Jul 17, 1998·Journal of Leukocyte Biology·M J Fenton, D T Golenbock
Dec 2, 1999·Nature·E MigliaccioP G Pelicci
Jul 21, 2000·IUBMB Life·V P Skulachev
Sep 7, 2000·Microbiology and Molecular Biology Reviews : MMBR·K Lewis
Jul 10, 2001·The Journal of Clinical Endocrinology and Metabolism·G S RothM A Lane
Aug 2, 2001·The Journal of Nutrition·J MatsuzakiY Nakano
Apr 27, 2002·Annals of the New York Academy of Sciences·Vladimir P Skulachev
May 29, 2002·Oncogene·Mirella TrineiPier Giuseppe Pelicci
Feb 7, 2003·Proceedings of the National Academy of Sciences of the United States of America·Claudio NapoliPierGiuseppe Pelicci
Apr 5, 2003·Neuroscience·P E BicklerD M Taylor
Jul 8, 2003·Science of Aging Knowledge Environment : SAGE KE·Karen Hopkin
Jul 28, 2004·Physiology & Behavior·L HartM K Oosthuizen
May 10, 2005·Science·Samuel E SchrinerPeter S Rabinovitch
Aug 10, 2005·Mechanisms of Ageing and Development·Blazej AndziakRochelle Buffenstein
Nov 4, 2005·Biochemistry. Biokhimii︠a︡·V I Padalko
Dec 13, 2005·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Rochelle Buffenstein
Jan 10, 2006·Annals of the New York Academy of Sciences·Walter Pierpaoli, Daniele Bulian
Apr 1, 1982·Plant Physiology·L D Noodén, B J Murray
Jun 14, 2006·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Alberto SanzGustavo Barja
Feb 27, 2007·Journal of Neuroscience Methods·Jun Xiao
Dec 2, 1977·Science·J Wodinsky
Oct 5, 2007·Kidney International·E Y PlotnikovD B Zorov
Apr 22, 2008·Cell·Yumiko ImaiJosef M Penninger
May 29, 2008·Aging Cell·Camille C Caldeira da SilvaAlicia J Kowaltowski
Sep 23, 2008·Nature Medicine·Heng DuShi Du Yan
Nov 11, 2008·Nature Genetics·Siegbert MelzerTom Beeckman
Nov 29, 2008·Biogerontology·Pilar CaroGustavo Barja
Jan 6, 2009·Biochemistry. Biokhimii︠a︡·L E BakeevaV P Skulachev
Jan 6, 2009·Biochemistry. Biokhimii︠a︡·V N AnisimovV P Skulachev
Jan 23, 2009·Biochimica Et Biophysica Acta·Vladimir P SkulachevDmitry B Zorov
Mar 25, 2009·Proceedings of the National Academy of Sciences of the United States of America·Mehmet SomelPhilipp Khaitovich
Nov 13, 2009·Neuroreport·John Larson, Thomas J Park
Jan 19, 2010·Proceedings of the National Academy of Sciences of the United States of America·Fedor F SeverinVladimir P Skulachev
Mar 3, 2010·Aging·Lidia A ObukhovaNatalia G Kolosova
Mar 6, 2010·Nature·Qin ZhangCarl J Hauser
Mar 24, 2010·Biochimica Et Biophysica Acta·Vladimir P SkulachevRenata A Zvyagilskaya
Mar 24, 2010·Proceedings of the National Academy of Sciences of the United States of America·Vincent Julien LecomteHenri Weimerskirch
Apr 7, 2010·Biochemistry. Biokhimii︠a︡·E Y PlotnikovD B Zorov
Citations
Apr 16, 2019·Rejuvenation Research·Si-Jun ZhaoXue-Mei Qin
May 30, 2019·Biology·Andrei SurguchovAlexei A Surguchev
Oct 9, 2019·Biogerontology·Piotr Paweł Chmielewski
Mar 1, 2018·Biochemistry. Biokhimii︠a︡·V N ManskikhA I Nikiforova
Jun 22, 2019·Biochemistry. Biokhimii︠a︡·A Yu RatushnyyL B Buravkova
Sep 21, 2018·Experimental and Therapeutic Medicine·Naichun JiKejing Lao
Apr 2, 2020·Aging·Vladimir P SkulachevVictor A Sadovnichii
Dec 13, 2019·Oxidative Medicine and Cellular Longevity·Konstantin G LyamzaevBoris V Chernyak
Feb 7, 2020·Physiology·Rochelle BuffensteinHolly M Brown-Borg
Nov 16, 2019·BioData Mining·Lev I RubanovVassily A Lyubetsky
Jun 27, 2020·Biochemistry. Biokhimii︠a︡·S S Sokolov, F F Severin
Mar 11, 2020·Proceedings of the National Academy of Sciences of the United States of America·Mikhail Y VyssokikhVladimir P Skulachev
Aug 3, 2019·European Journal of Medicinal Chemistry·Lucia BiasuttoMario Zoratti
Feb 24, 2021·The Ocular Surface·Jeremias G Galletti, Cintia S de Paiva
May 1, 2021·Antioxidants·Lindsey J Shinn, Sarita Lagalwar