Programmed cell death in the human ovary

Minerva ginecologica
Serena MarcozziFrancesca G Klinger

Abstract

During a woman's reproductive life, only about 400 primordial follicles will develop into a preovulatory follicle and undergo ovulation, releasing an oocyte available for fertilization. The process of formation and selection of these follicles is complex and involves a multistep process characterized by a balance between survival and death of the oocytes and the surrounding follicular cells. Although the mechanisms underlying such process are not completely clarified yet, it is common idea that they can occur through various types of programmed cellular death (PCD). Since atresia is the principal destiny of the ovarian follicles, it is relevant to understand how this process takes place and how it is regulated. In this review, after a summary description of folliculogenesis in humans, the main mechanisms of atresia reported to occur during folliculogenesis from birth to adult age, in the human ovary and in other mammals when appropriate, are described.

References

Nov 1, 1978·Clinics in Endocrinology and Metabolism·H PetersJ Grinsted
Jan 1, 1976·Journal of Reproduction and Fertility·R Himelstein-BrawM Faber
Oct 1, 1991·The Anatomical Record·A ForaboscoV F Ferrario
Jun 1, 1991·Biology of Reproduction·A N Hirshfield
Jan 1, 1991·International Review of Cytology·A N Hirshfield
Jan 1, 1997·Annual Review of Physiology·A Kaipia, A J Hsueh
Aug 28, 1997·The New England Journal of Medicine·C Matthews, V K Chatterjee
Sep 1, 1996·Reviews of Reproduction·J L Tilly
Oct 31, 1998·Reproduction, Nutrition, Development·M A Driancourt, B Thuel
Nov 13, 1998·Proceedings of the National Academy of Sciences of the United States of America·A DierichP Sassone-Corsi
Dec 22, 1999·The Anatomical Record·J Singh, G P Adams
Apr 28, 2001·Molecular and Cellular Endocrinology·E NilssonM K Skinner
Nov 21, 2001·Nature Reviews. Molecular Cell Biology·J L Tilly
Feb 28, 2002·Endocrinology·Alexandra L L DurlingerAxel P N Themmen
Mar 26, 2002·Molecular and Cellular Endocrinology·Eric E NilssonMichael K Skinner
Jul 11, 2002·The Journal of Clinical Endocrinology and Metabolism·P S HartleyR A Anderson
Nov 6, 2002·Reproduction : the Official Journal of the Society for the Study of Fertility·Alexandra L L DurlingerAxel P N Themmen
Nov 29, 2002·Frontiers in Bioscience : a Journal and Virtual Library·Jin-Yi JiangBenjamin K Tsang
Oct 22, 1963·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·T G BAKER
Jan 1, 1964·Cytogenetics·S OHNO, J B SMITH
Dec 4, 2003·Human Reproduction·Raffaella DepaloLuigi Selvaggi
Jul 23, 2004·Biology of Reproduction·Kara L BrittJock K Findlay
Dec 1, 2004·Proceedings of the National Academy of Sciences of the United States of America·Xiaoping MaT Rajendra Kumar
Feb 12, 2005·Human Reproduction Update·Mahmoud R Hussein
Mar 12, 2005·Domestic Animal Endocrinology·Huanmin Zhou, Yong Zhang
Apr 1, 1997·Cell Death and Differentiation·M De Felici

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