Progress in capillary electrophoresis coupled to matrix-assisted laser desorption/ionization - time of flight mass spectrometry

Electrophoresis
Christian W HuckGünther K Bonn

Abstract

In this review the most important techniques developed to hyphenate CE to MALDI-TOF-MS are summarized. The principles of the different interfaces and ways to solve the hyphenation problem are explained and discussed in detail. The most important applications especially in the proteomic field are reviewed, and the advantages of CE-MALDI-TOF-MS for the analysis of these compounds compared to other techniques such as ESI-MS are exhaustingly discussed from a critical point of view. CE coupled to MALDI-TOF-MS has started to overpass traditionally used CE-coupling techniques, especially CE-ESI-MS, offering the possibility to analyze samples of interest even weeks after CE analysis and using multiplexing systems for high-sample throughput.

References

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Citations

Sep 11, 2012·Journal of Chromatography. a·Michal HolčapekMiroslav Lísa
May 23, 2012·Journal of Proteomics·Rawi RamautarOleg A Mayboroda
Aug 3, 2010·Journal of Pharmaceutical and Biomedical Analysis·Claudia DesiderioMassimo Castagnola
Mar 23, 2010·Journal of Chromatography. a·Ondrej Pes, Jan Preisler
Jan 17, 2009·Journal of Chromatography. a·Kati HelmjaMerike Vaher
Jun 15, 2007·Journal of Chromatography. a·Rob HaselbergGovert W Somsen
Mar 3, 2007·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Dmitri Y Boudko
May 15, 2009·Electrophoresis·Aline StaubJean-Luc Veuthey
Jun 12, 2009·Electrophoresis·Christian W Klampfl
Sep 2, 2009·Electrophoresis·Zhaowei ZhangBi-Feng Liu
May 16, 2008·Journal of Separation Science·Guillaume L ErnyAlejandro Cifuentes
Oct 27, 2007·Electrophoresis·Guillaume L ErnyAlejandro Cifuentes
Apr 15, 2008·Electrophoresis·Miguel HerreroAlejandro Cifuentes
Apr 12, 2007·Electrophoresis·Chiu-Tang ChienGuor-Rong Her
Feb 28, 2007·Journal of Mass Spectrometry : JMS
Dec 7, 2007·Electrophoresis·Vladislav Dolník
Jan 22, 2011·Mass Spectrometry Reviews·Pawel L UrbanRenato Zenobi
May 3, 2014·Biomedical Chromatography : BMC·Drupad K Trivedi, Ray K Iles
Aug 28, 2014·Talanta·Bonnie Jaskowski HugeNorman J Dovichi
Feb 1, 2021·Analytica Chimica Acta·Thomas ThemelisSebastiaan Eeltink

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