Progress in oncology biosimilars till 2020: Scrutinizing comparative studies of biosimilar monoclonal antibodies.

Journal of Oncology Pharmacy Practice : Official Publication of the International Society of Oncology Pharmacy Practitioners
Aqsa SafdarMuhammad Zaman

Abstract

Stupendous elevation in the healthcare costs has followed with the inception of the current unconventional options of treatment available for cancer patients. There is a dire need of innovative financing approaches to lessen the financial load on healthcare system. Biosimilars are biological drugs consisting of an active ingredient from a reference biological drug that has a great potential of relieving financial load. Strict requirements from regulatory point of view are required as biosimilars are exceedingly similar to but not identical to the reference product. This provides with a certainty that no consequential differences from clinical point of view as compared to the respective biologics exists with regards to efficacy, safety and purity. Safety and effectiveness of biosimilars have been disclosed since more than 10 years of affirmations. However, there is a need to educate the healthcare professionals to abolish potential misconceptions and coalesce biosimilars into regular clinical practice. The present review focuses on providing an overview of regulatory aspects and requirements for biosimilars, the main challenges in the selection and development of biosimilars and the economic impact and financial savings observed...Continue Reading

References

Oct 13, 2006·Nature Biotechnology·Gary Walsh, Roy Jefferis
Jan 18, 2012·Targeted Oncology·Paul Cornes
Oct 9, 2013·Health Affairs·Francis MegerlinJean-Hugues Trouvin
Oct 18, 2013·The Lancet Oncology·Ramon Luengo-FernandezRichard Sullivan
Jan 15, 2016·American Journal of Therapeutics·Leah IsakovIra Allen Jacobs
Mar 18, 2016·Cancer Chemotherapy and Pharmacology·Beverly KnightReginald Ewesuedo
May 3, 2016·Cancer Treatment Reviews·Hope S RugoIra Jacobs
Sep 3, 2016·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Bengt JönssonNils Wilking
Aug 27, 2017·Biotechnology and Bioengineering·Carol F KirchhoffArindam Bose
Sep 13, 2017·Journal of Oncology Practice·Gary H Lyman
Nov 3, 2017·Journal of Global Oncology·Rakesh Chopra, Gilberto Lopes
Dec 30, 2017·The Oncologist·Fadi FarhatSimon Abi Aad
Feb 16, 2018·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·X PivotJ Lim
Jun 2, 2018·Future Oncology·Yelena Y JanjigianMark Latymer
Jun 22, 2018·British Journal of Clinical Pharmacology·Cornelius F WallerEduardo J Pennella
Aug 28, 2018·World Journal of Clinical Cases·Flyn Kaida-YipDinesh Vyas
Sep 7, 2018·European Journal of Clinical Pharmacology·J O'CallaghanB T Griffin
Nov 10, 2018·Cancer Management and Research·Kashyap B PatelSelwyn Fung
Jan 9, 2019·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Nicholas ThatcherVladimir Hanes
Mar 10, 2019·BioDrugs : Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy·Sang-Heon ChoJae-Gook Shin
Apr 25, 2019·BioDrugs : Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy·Xiaoyun WuLi Zhang
Aug 25, 2019·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Xavier PivotChul Kim
Oct 16, 2019·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·Sandra CuellarPatrick Medina
Jan 14, 2020·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Hans-Christian KolbergVladimir Hanes
Feb 3, 2020·The Lancet Oncology·Hui-Yao HuangJie He
Feb 15, 2020·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Justin StebbingHope S Rugo
Apr 10, 2020·Journal of Oncology Pharmacy Practice : Official Publication of the International Society of Oncology Pharmacy Practitioners·Emma ForemanAlexandre Chan
Apr 10, 2020·Journal of Oncology Pharmacy Practice : Official Publication of the International Society of Oncology Pharmacy Practitioners·Chia Jie TanAlexandre Chan
Apr 10, 2020·Journal of Oncology Pharmacy Practice : Official Publication of the International Society of Oncology Pharmacy Practitioners·Alexandre ChanEmma Foreman

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