Progress on the Chemical Constituents Derived from Glucosinolates in Maca (Lepidium meyenii)

Natural Products and Bioprospecting
Yan-Jie HuangMing-Hua Qiu

Abstract

Maca (Lepidium meyenii Walp.), a famous food supplement, has drawn an unprecedented international interest over the last two decades. It was assumed that glucosinolates, macamides, macaenes, and alkaloids are the main bioactive components of Maca before. Recently, a series of novel thiohydantoins which generally exhibit a variety of activities have been isolated from Maca. This review focuses on the progress on the main bioactive components of Maca and their biosynthetic pathway, which indicates that macamides, thiohydantoins, and some alkaloids may originate from glucosinolates. Interestingly, thiohydantoins from Maca are the first type of thiohydantoin derivatives to be found from a natural source and may contribute to some significant effects of Maca.

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Citations

Feb 15, 2020·Advanced Biomedical Research·Mahbobeh MontazeriSomayeh Shahani
Sep 28, 2020·Pharmacology & Therapeutics·Anutthaman ParthasarathyKarunakaran Kalesh
Jun 1, 2021·Dermatologic Clinics·Glynis Ablon
Jun 3, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Mengya JiaoHui Yin
Aug 28, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Ranran ZhangMinghua Qiu
Oct 1, 2021·Journal of Agricultural and Food Chemistry·Kartiko Arif PurnomoFang-Rong Chang
Dec 9, 2020·Food Research International·Hongkang ZhuHe Qian

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