PMID: 8594576Jan 1, 1996Paper

Progress with the PRINTS protein fingerprint database

Nucleic Acids Research
T K AttwoodD J Parry Smith

Abstract

PRINTS is a compendium of protein motif 'fingerprints' derived from the OWL composite sequence database. Fingerprints are groups of motifs within sequence alignments whose conserved nature allows them to be used as signatures of family membership. To date, 400 fingerprints have been constructed and stored in Prints, the size of which has doubled in the last year. The current version, 9.0, encodes approximately 2000 motifs, covering a range of globular and membrane proteins, modular polypeptides, and so on. Fingerprints inherently offer improved diagnostic reliability over single motif methods by virtue of the mutual context provided by motif neighbours. PRINTS thus provides a useful adjunct to the widely used PROSITE dictionary of patterns. The database is now accessible via the Database Browser on the UCL Bioinformatics server at http://www.biochem.ucl.ac.uk/bsm/dbbrowser .

References

Oct 1, 1992·Computer Applications in the Biosciences : CABIOS·D J Parry-Smith, T K Attwood
Jul 9, 1992·Nature·M S BoguskiG S Michaels
Dec 11, 1991·Nucleic Acids Research·S Henikoff, J G Henikoff
Oct 15, 1991·Biochemical and Biophysical Research Communications·D R FlowerT K Attwood
Oct 5, 1990·Journal of Molecular Biology·S F AltschulD J Lipman
Oct 1, 1985·Scientific American·R F Doolittle
May 1, 1993·Protein Science : a Publication of the Protein Society·D R FlowerT K Attwood
Sep 1, 1994·Nucleic Acids Research·D A BensonJ Ostell
Sep 1, 1994·Nucleic Acids Research·A Bairoch
Jul 1, 1994·Protein Engineering·T K Attwood, M E Beck
Mar 1, 1994·Protein Science : a Publication of the Protein Society·E L Sonnhammer, D Kahn
Feb 1, 1994·Protein Engineering·T K Attwood, J B Findlay
Jul 1, 1993·Nucleic Acids Research·W C BarkerA Tsugita
Feb 1, 1993·Protein Engineering·T K Attwood, J B Findlay

❮ Previous
Next ❯

Citations

Jun 1, 1996·Current Opinion in Structural Biology·P Bork, E V Koonin
Jan 1, 1996·Journal of Computational Biology : a Journal of Computational Molecular Cell Biology·C H WuH L Chen
Jan 1, 1997·Nucleic Acids Research·T K AttwoodD J Parry-Smith
Jan 1, 1997·Nucleic Acids Research·P Fábián, K N Degtyarenko
Mar 15, 1997·Nucleic Acids Research·F B PerlerE Adam
May 1, 1996·Trends in Biochemical Sciences·A D MichieT K Attwood
May 1, 1997·Journal of Chemical Information and Computer Sciences·T K AttwoodC Worledge

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2021 Meta ULC. All rights reserved