Progression in venous pathology

Phlebology
F Pannier, E Rabe

Abstract

To review epidemiologic data on progression of venous pathology in varicose veins and from varicose veins towards chronic venous insufficiency. We searched Medline and PubMed for epidemiologic studies concerning progression of venous pathology. The data suggest that reflux progression may develop from segmental to multisegmental superficial reflux. In younger age, reflux in tributaries and non-saphenous veins is more frequent. In older age, more saphenous reflux develops and more proximal sites seem to be affected. A high proportion of uncomplicated varicose vein (C2) develops skin changes and chronic venous insufficiency (C3-C6). Significant risk factors for the progression of varicose vein towards venous leg ulcers are skin changes, corona phlebectatica, higher body mass index and popliteal vein reflux. During a 13.4-year follow-up period, 57.8% (4.3%/year) of all chronic venous disease patients showed progression of the disease. Studies on the progression of venous pathology show a high progression rate of chronic venous disease. More follow-up studies are still needed to get better information about the risk of varicose vein patients for progression to venous leg ulcers and to answer the question which patients may benefit ...Continue Reading

References

Feb 1, 1994·The British Journal of Surgery·M J Callam
Dec 31, 1997·Journal of Vascular Surgery·N LabropoulosW H Baker
Mar 16, 2005·Journal of Vascular Surgery·Nicos LabropoulosFred N Littooy
Dec 6, 2006·Journal of Vascular Surgery·Alberto CaggiatiMaria Cristina Acconcia
Mar 10, 2009·Journal of Vascular Surgery·Nicos LabropoulosApostolos K Tassiopoulos
Jun 6, 2009·Journal of Vascular Surgery·Lindsay RobertsonFrancis G Fowkes
Mar 30, 2010·Journal of Vascular Surgery·Theodoros I KostasAsterios N Katsamouris

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Citations

Feb 27, 2016·Clinical Imaging·Benjamin L YamNeil M Khilnani
Jun 30, 2018·Phlebology·Aleksandra StaniszewskaAlun H Davies
Feb 14, 2019·Advances in Therapy·Andrew N Nicolaides, Nicos Labropoulos
Dec 31, 2020·Journal of Clinical Medicine·Joseph D RaffettoFerdinando Mannello

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